6311 Medical Science I
"Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA"
Mentor: Dr. Nils Walter
Discussant: Charlie Knox
6311 Medical Science I
"Cas9 specifies functional viral targets during CRISPR-Cas Adaptation"
Mentor: Dr. Yan Zhang
Discussant: Brian Hardaway
6311 Medical Science I
"Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk"
Mentor: Dr. Jim Morrissey
Discussant: Christine Ziegler
6311 Medical Science I
Title: "Membrane proteins bind lipids selectively to modulate their structure and function"
Mentor: Dr. Jim Morrissey
Discussant: Fabienne Birkle
6311 Medical Science I
Title: "Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration"
Mentor: Dr. Michael Uhler
Discussant: Divyani Paul
6311 Medical Science I
Title" "Novel insight into streptozotocin-induced diabetic rats from the protein misfolding perspective"
Advisor: Dr. Ruthann Nichols
Discussant: Alex Fischbach
6311 Medical Science I
Title: "AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer"
Advisor: Dr. Ruthann Nichols
Discussant: Shahzaib Chughtai
6311 Medical Science I
"Computationally designed high specificity inhibitors delineate the roles of Bcl2 family proteins in cancer"
Mentor: Dr. Yang Zhang
Discussant: Jordan Hochstetler
6311 Medical Science I
Title: "Regioselective para -Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase"
Mentor: Dr. Neil Marsh
Discussant: Robin Pearce
6311 Medical Science I
Title: "Depletion of coagulation factor FXII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice"
Mentor: Dr. Jim Morrissey
Discussant: April Kaneshiro
