Ajit Joglekar

Associate Professor
Research Focus: Cell division, genome stability, signal transduction and signaling, bioengineering, cancer cell biology

3067 BSRB 
109 Zina Pitcher Place
Ann Arbor MI 48109-2200

734-764-2474

Areas of Interest

During cell division, cells divide their duplicated chromosomes equally between the two daughter cells by building a complex protein machine known as the kinetochore. How does this machine work at the molecular and biophysical level? What is the effect of defective kinetochore design and function in cancer cell biology? What are the operational and evolutionary constraints that shape its design? Can we build/reverse engineer a kinetochore-like machine that drives the equal division of synthetic chromosomes? Such a reverse engineered kinetochore can provide the transformative technology that will facilitate gene therapy.

Associated Grad Programs

Cell & Developmental Biology, Cellular & Molecular BiologyBiophyics

Credentials

  • University of North Carolina-Chapel Hill, Postdoctoral Fellow, 12/2010
  • University of Michigan, Ph.D., 06/2004
  • University of Pune, BEng, 06/1999

Published Articles or Reviews

Web Sites