Careers

Faculty Positions in Genetics at the University of Michigan

Location:

Ann Arbor, Michigan

Type:

Full Time - Experienced

Years of Experience:

Less than 2

Categories:

Academic / Faculty, Academic / Research

The Department of Human Genetics at the University of Michigan Medical School seeks to fill multiple tenure-track faculty positions at the Assistant and Associate Professor level. Recruited faculty members will join a cohesive and highly interactive community of 36 investigators with research programs in diverse areas of genetics. Faculty in the Department of Human Genetics employ many different approaches to address basic and applied questions in genetics, and we welcome applicants with diverse research interests in this field. More information about the Department can be found at https://medicine.umich.edu/dept/human-genetics. The Department of Human Genetics was established at the University of Michigan in 1956 by James V. Neel and is recognized as the first department dedicated to human genetics in the United States. The Department integrates well with genetic research being performed in the nine basic science and twenty clinical departments in the Medical School, as well as with departments in the School of Public Health and the College of Literature, Science, and the Arts. The undergraduate and medical school campuses are located in Ann Arbor, which is frequently ranked as one of the best cities to live in the United States.  Candidates with a PhD and/or MD degree and exceptional research accomplishments should submit a curriculum vitae, a three-page description of research experience with an emphasis on future plans, and three letters of recommendation. In addition, teaching and DEI (diversity, equity, and inclusion) statements are welcome. All materials should be submitted to https://apply.interfolio.com/66138. The search committee will review applications as they are received. Women and underrepresented minorities are encouraged to apply. The University of Michigan is supportive of the needs of dual career couples and is an equal opportunity and affirmative action employer.

  • PhD and/or MD degree
  • Curriculum vitae
  • Three-page description of research experience with an emphasis on future plans
  • Three letters of recommendation
  • Teaching and DEI (diversity, equity, and inclusion) statements are welcome 

 Please send any questions about the opening to Anthony Antonellis: antonell@umich.edu

Postdoctoral Fellow in Genetics at the University of Michigan

Location:
Ann Arbor, Michigan

Type:
Full Time

Categories:
Academic / Research, Research Fellows

Job Summary

The Kalantry Lab in the Department of Human Genetics at the University of Michigan Medical School is seeking a postdoctoral fellow to join our interdisciplinary and highly interactive laboratory team focused on elucidating principles of epigenetic inheritance primarily, but not exclusively, through the study of X-chromosome inactivation.  X-inactivation is an evolutionarily conserved paradigm of epigenetic regulation that equalizes X-linked gene expression between male and female mammals by silencing genes on one of the two X-chromosomes in females.  X-inactivation lies at the nexus of functional long noncoding (lnc) RNAs and chromatin-modifying factors. 

The Kalantry Lab has discovered new lncRNAs and identified chromatin modifying proteins with previously unknown functions in X-inactivation.  Projects involve genetically and biochemically testing lncRNAs and chromatin modifiers in initiating and/or maintaining X-inactivation in cultured stem cells and in mice as well as discovering novel factors and mechanisms underlying X-inactivation.  Postdoctoral fellows will have opportunities to take projects with them to their independent positions. 

Key Responsibilities

  • Work closely with others in the laboratory to genetically and epigenetically dissect X-chromosome inactivation in a variety of model systems, including mouse, rat, and human stem cells and mouse and rat embryos.
  • Take initiative and develops new concepts and techniques.
  • Read the relevant scientific literature deeply. 
  • Attend and presents seminars and participates in joint lab meetings.
  • Prepare manuscripts for publication and presents findings at national meetings.

Required Qualifications

  • Ph.D. in genetics and/or epigenetics or related fields.
  • Expertise in molecular biology, cell culture, and/or biochemistry.
    • Highly motivated, organized individual with a demonstrated track record of innovation and independent direction.
    • Ability to work collaboratively, take initiative, and complete projects. 
    • A strong publication record with one or more first-author publication(s).

 Desired Qualifications

  • Ability to analyze high-throughput datasets. 
  • Experience with advanced statistical methods.

Background Screening

The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.

How to Apply

To apply, qualified applicants must submit an application to the University of Michigan Job Board (ID 176091) that should include the following:

  • Cover letter stating your scientific background, interests, and career goals
  • Curriculum vitae or resume
  • Contact information for references

Please direct any questions about the position to kalantry@umich.edu.

Kalantry Lab website: https://kalantry.lab.medicine.umich.edu

Postdoctoral Fellow in Genetics at the University of Michigan

Location:
Ann Arbor, Michigan

Type:
Full Time

Categories:
Academic / Research, Research Fellows

Job Summary

A postdoctoral research fellowship position is available in the laboratory of Dr. Jacob Kitzman in the Department of Human Genetics and Department of Computational Medicine and Bioinformatics. Our group develops new genomics technologies to detect and study the functional impacts of genetic variation upon traits in health and disease. The specific focus of this position will be to develop deep ‘functional maps’ of human disease genes using cutting-edge, high-throughput experimental approaches including deep mutational scanning and CRISPR domain scanning.

Key Responsibilities

The successful candidate will establish mammalian cell culture and organoid functional assays for several genes, adopting and improving approaches developed in our lab and elsewhere. The candidate will be expected to gain familiarity with the primary literature in areas relevant to the genes selected for functional studies, as well as in sequencing and genome editing technologies generally.

Finally, the applicant will be expected to contribute to supervision of students and technicians to work collaboratively on this and related projects. 

Desired Qualifications

This position requires a highly motivated, organized individual with a demonstrated track record of innovation and independent direction. Applicant must hold a Ph.D. in a genomics-related field such as Genetics, Molecular Biology, Biochemistry, or Bioinformatics. Extensive experience in standard molecular biology, cloning techniques, and tissue culture techniques is required. Prior experience with genome editing (e.g., using CRISPR/Cas or TALEN technologies) and massively parallel sequencing (e.g., Illumina) is desirable. Some experience with biological data analysis tools and general bio-computing skills (e.g., Linux, python, jupyter notebook, R) is required.

Background Screening

The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.

How to Apply

To apply, qualified applicants must submit an application to the University of Michigan Job Board (ID 173029) that should include the following:

  • Cover letter stating your scientific background, interests, and career goals
  • Curriculum vitae or resume
  • Contact information for references

Interested candidates may email a C.V. to Dr. Kitzman (his surname followed by first initial at umich.edu), in addition to applying online.