October 2021 - Endocrine Society Publications
Read our special collection of journal articles, published in 2020-2021, focused on neuroendocrinology! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Endocrinology, Sucquart and colleagues report that mice modeling polycystic ovary syndrome treated with a neurokinin 3 receptor antagonist demonstrated changes affecting metabolic status but no change to reproductive defects. Zhang and coauthors review new evidence about the role of estrogens in neural circuits that control temperature, of possible relevance to treating hot flashes. Bozadjieva-Kramer et al. use a viral gene-knockout technology to demonstrate the significance of pituitary adenylate cyclase activating polypeptide, expressed in the mediobasal hypothalamus, in sympathetic nervous system coordination of metabolism. Alhadeff discusses recent insights, based on monitoring of in vivo neural activity, that shed light on how signals from the gut influence feeding.
In Endocrine Reviews, Jais and Brüning review the role of the arcuate nucleus of the hypothalamus in controlling adiposity. Manoogian and coauthors discuss the potential of time-restricted eating to counter obesity in humans, and Srirangam Nadhamuni and Korbonits provide insights into genetic and epigenetic mechanisms of pituitary tumorigenesis.
In Journal of the Endocrine Society, Haydar Ali Tajuddin and colleagues review the expression and effects of estrogen receptors in nonfunctioning pituitary neuroendocrine tumors. Boharoon and coauthors describe favorable results of rituximab treatment in a small number of patients with igG4-related hypophysitis. And Vazquez and colleagues assess increasing recognition of epigenetic factors in the control of puberty, especially in Kiss1 neurons.
In JCEM, Jacobson and colleagues report that prenatal exposure to bisphenols and phthalates is associated with maternal postpartum depression, with disruption of neurosteroids a likely explanation. Alexis Vishnopolska et al. describe an analysis of pathogenic gene variants in pediatric patients with neuroendocrine disorders. Chambers and colleagues use UK Biobank data to establish a link between thyroid status and gray matter volume, particularly in the cerebellum and pallidum. And Feng et al. confirm an increased risk of Parkinson’s disease in osteoporosis patients, particularly women.