Kanakadurga Singer

Kanakadurga Singer, M.A., M.D.

Valerie Castle Opipari, M.D. Professor of Pediatrics
Associate Professor, Department of Pediatrics - Division of Pediatric Endocrinology and Department of Molecular and Integrative Physiology
Immunology Program Faculty Ally
Assistant Dean for Tenure Track Faculty
Lab Website
Dept. Website
Accepting Students?
Yes

Biography

Dr. Singer is an Associate Professor in Pediatric Endocrinology. She received a B.A. M.A degree from Johns Hopkins University and completed her M.D. degree in 2006 from the University of Michigan Medical School. She also completed her Pediatrics residency and her Pediatric Endocrinology Fellowship at the University of Michigan. She joined as a faculty member in 2012 and has been supported by grants from the American Heart Association, the Taubman Emerging Scholars Program, the Janette Ferrantino Junior Investigator Award, and grants from NIH NIDDK. She serves as the Assistant Dean for Tenure Track Faculty.

Research Interests

Research in the Singer Lab is focused on understanding the influence of diet-induced obesity on hematopoiesis and the generation of activated macrophages that lead to metabolic disease. Understanding the immune physiology after high fat diet exposure in mice and translating these findings to pediatric obesity will lead to future therapeutic and dietary interventions. Current projects in the laboratory focus on

1. Sexually dimorphic inflammatory responses to high fat diet

2. Mechanisms driving hematopoietic stem cell myeloid differentiation after high fat diet exposure. This work in mouse models uses bone marrow transplantation, stem-cell analysis techniques, and metabolic profiling.

3. Translational studies understanding metabolic inflammation in pediatric populations.

 

Research Opportunities for Rotating Students

1. Sexually dimorphic inflammatory responses to high fat diet

2. Mechanisms driving hematopoietic stem cell myeloid differentiation after high fat diet exposure. This work in mouse models uses bone marrow transplantation, stem-cell analysis techniques, and metabolic profiling.

3. Translational studies understanding metabolic inflammation in pediatric populations.

Publications

http://orcid.org/0000-0001-8278-3800

Current Student Advisees