Gabrielle Entrup

Immunology Program Graduate Student Candidate
NIH - F31 Fellowship

Biography

A West Michigan native, Gabrielle earned her Bachelors of Science degree in Microbiology from Michigan State University’s Honors College in 2019. She also completed an additional major in Genomics and Molecular Genetics through the College of Natural Science. Her first research project was with Dr. Jim Tiedje uncovering new species of dioxin degrading bacteria. After finding her passion for immunology, she began a research project with Dr. Andrew Olive studying genetic mechanisms underlying regulation of MHCII in chronic infections such as Mycobacterium tuberculosis and Chlamydia trachomatis.

After graduation, Gabrielle enthusiastically joined PIBS in Fall 2019. In April 2020, she joined both Durga Singer and Beth Moore's labs. She is also completing a certificate in Diversity, Equity, and Inclusion in Teaching.

Research Interests

Gabrielle’s research interests are in host-pathogen interactions, innate immunity, and lung biology. Her project is focused on understanding the innate immune cell functional and recruitment defects that lead to increased morbidity and mortality seen in patients with obesity following pulmonary bacterial infections. Her work has led her to the role of PGE2 in alveolar macrophage ability to phagocytose bacteria.

Techniques Used

Flow cytometry, mouse infection models, mouse obesity models, sex differences in immunology, qPCR, nucleic acid extraction, bone marrow transplant

Awards

Miller Award For Outstanding Immunology Research 2023

M-BRISC Best Poster Award 2023

NHLBI F31 Recipient Elected co-chair for 2024

Gordon Research Seminar Biology of Acute Respiratory Infection Immunology Program Outstanding Graduate Service Award 2021

University of Michigan Molecular Mechanisms in Microbial Pathogenesis T32 Trainee 2020

Michigan State University Honors College Member 2015-2019

Michigan State University Honors College Service Award 2019

Abstracts

2023 Obesity Inhibits Innate Immune Functions During Pseudomonas aeruginosa Pneumonia. Caswell Diabetes Institute Symposium. Poster and selected for short talk in Data Blitz. Ann Arbor, MI.

2023 Sexual Dimorphism in Clearance of Pseudomonas aeruginosa in Obese Mice. M-BRISC 2nd Annual Symposium. Poster. Ann Arbor, MI

2022 Obesity Inhibits Innate Immune Functions During Pseudomonas aeruginosa Pneumonia. Gordon Research Seminar & Conference Biology of Acute Respiratory Infection. Poster. Ventura, CA

2022 Obesity Inhibits Innate Immune Functions During Pseudomonas aeruginosa Pneumonia. Immunology Graduate Program Annual Retreat. Poster. Ann Arbor, MI.

2022 Obesity Inhibits Innate Immune Functions During Pseudomonas aeruginosa Pneumonia. American Association of Immunologists Conference. Poster. Portland, OR.

2021 Obesity Inhibits Innate Immune Functions During Pseudomonas aeruginosa Pneumonia. Immunology Graduate Program Annual Retreat. Poster. Ann Arbor, MI.

2020 Analysis of MRSA Pulmonary Infection in Diabetic Mice. Mucosal Immunology Pathology Symposium. Poster. Ann Arbor, MI.

Hobbies and Extracurricular Activities

When I'm not in lab you can find me volunteering at the Humane Society of Huron Valley or walking/running/volunteering at Lillie parkrun. I enjoy finding great happy hour spots and hanging out with my husband and two dogs, Duke and Echo.