Cancer Immunology & Immunotherapy

We study the human cancer microenvironment, the role of gut microbiota and inflammation in carcinogenesis, oncogenic regulators of innate immunity, molecular mechanisms underlying tumor tolerance, and metabolic rewiring in cancer. In the immunotherapy arena, we have expertise in T cell-based approaches to cancer immunotherapy, nanovaccines against cancers and in tumor imaging. The University of Michigan is also home to the Rogel Cancer Center with a robust research program in the areas of cancer Immunology and Immunotherapy.