Michael D. Green, MD, PhD

Assistant Professor, Department of Radiation Oncology
Attending Physician, Radiation Oncology, Ann Arbor VA
Accepting Students?
Yes

Biography

Dr. Green received his medical and graduate degrees from the Icahn School of Medicine at Mount Sinai in New York. He undertook postgraduate clinical training in Radiation Oncology at the University of Michigan, and was a chief resident in the program. He undertook postdoctoral training in tumor immunology with Weiping Zou at the University of Michigan.

Research Interests

The Green laboratory aims to accelerate progress in cancer care by effectively integrating immunotherapy into treatment paradigms. Our laboratory utilizes expertise in quantitative immunophenotyping, quantitative image analysis, programmed cell death, and oxidized lipidomics to advance the fields of radiobiology, radiomics, and tumor immunology. We seek to define and harness the determinants of inflammation which shape anti-tumoral immunity and influence cancer therapy efficacy. In particular, we focus on understanding the molecular, metabolic, and cellular checkpoints which alter CD8+ T effector cell trafficking and function in the tumor microenvironment. We conduct clinical, translational, and preclinical studies that allow us to develop novel therapeutic strategies to better treat cancer patients.

Research Opportunities for Rotating Students

Recruiting students for multiple projects related to ferroptosis, hepatic immune tolerance, and determinants of immunotherapy and radiotherapy efficacy.