Monday, March 18, 2024

Origins of neural diversity in the vertebrate brain — Lessons from Drosophila

2:00 PM to 3:00 PM

LSI Library

This seminar featuring Jorge García Marqués, Ph.D. (Cajal Institute – CSIC), is hosted by the Life Sciences Institute.

Jorge García Marqués, Ph.D.

Group Leader, The Neurorigins Lab
Cajal Institute – CSIC
Madrid, Spain

Jorge graduated in Biological Sciences from the Complutense University of Madrid in 2005. For his PhD, he studied how different astroglial populations emerged during development in the mouse cerebral cortex. Jorge designed and optimized Star Track, a method based on the expression of combinations of fluorophores to specifically mark different lineages of astrocytes and NG2 cells. After stays at Yale University (USA) and the University of Geneva (Switzerland), Jorge received his PhD in Neuroscience from the Autonomous University of Madrid in 2012.

In 2014 Jorge joined Tzumin Lee’s lab at Janelia Research Campus (Howard Hugues Medical Institute) for his postdoc. There he developed an innovative CRISPR/Cas9-based technology for the study of neuronal lineages in Drosophila: 1) CaSSA, to gain genetic access to specific neural progenitors based on the genetic intersection of different markers, and 2) CLADES, to mark neurons generated at different times with distinct combinations of fluorescent markers that follow a temporal sequence. Jorge moved to Spain in 2020 funded by a Marie Curie Individual Fellowship to work in Marta Nieto’s lab (CNB-CSIC). After two years studying neural progenitor diversity in the mouse cerebral cortex, Jorge obtains a Ramon y Cajal contract to open his lab at the Cajal Institute in 2022.