Brendon O. Watson, M.D., Ph.D.

Michigan Neuroscience Institute Affiliate
Assistant Professor, Department of Psychiatry

Biomedical Science Research Building
Room 5059
Ann Arbor MI 48109-5720


Areas of Interest

Dr. Watson's lab uses electrophysiology and optogenetics to observe and manipulate dozens of neurons simultaneously in both head-fixed and freely-behaving rodents in order to answer questions aimed both at a fundamental neurobiological understanding of the cortical states and dynamics as well as the role of cortex in disease. We use an approach informed by an understanding of neuronal microcircuit dynamics, macrocircuit connectivity, and organism-level behavior to connect between the level of single neurons, networks of those neurons, and animal behavior.

Clinical Interests

  • Mood disorders
  • Anxiety disorders
  • Rapid-acting antidepressants including ketamine


  • B.A., Biology, Cornell University (2000)
  • Ph.D., Neurobiology and Behavior, Columbia University (2009)
  • M.D. Columbia Univ. College of Physicians & Surgeons (2009)

Published Articles or Reviews

Web Sites