Areas of Interest
Dr. Mashour is an anesthesiologist and NIH-funded neuroscientist who is internationally recognized for his work on consciousness. He studies consciousness using computational models, experimental models, translational studies in healthy volunteers, and clinical research in surgical patients. He also has expertise in promoting translational research.
Specifically, his interests lie in:
- multidisciplinary approaches to the study of consciousness (Network mechanisms of consciousness and unconsciousness, intraoperative awareness and metrics of consciousness, and interfaces of sleep neurobiology and general anesthesia), and
- Perioperative neurologic outcomes (e.g., stroke, nerve injury, postoperative visual loss)
Credentials
Mashour received his medical degree and doctorate in neuroscience from Georgetown University and studied neuroscience as a Fulbright Scholar in Berlin and Bonn. After completing residency and chief residency at Harvard Medical School and Massachusetts General Hospital, he pursued a neurosurgical anesthesiology fellowship at Michigan Medicine. In 2007, Mashour was appointed assistant professor in the departments of anesthesiology and neurosurgery, with an additional faculty appointment in the Neuroscience Graduate Program. He was promoted to professor in 2017 and appointed professor of pharmacology in 2021.
Published Articles or Reviews
- Duan Li, Phillip Vlisides, George Mashour. Dynamic reconfiguration of frequency-specific cortical coactivation patterns during psychedelic and anesthetized states induced by ketamine. 2022, NeuroImage – Article.
- Zirui Huang, Vijay Tarnal, Phillip Vlisides, Ellen Janke, Amy McKinney, Paul Picton, George Mashour, Anthony Hudetz. Anterior insula regulates brain network transitions that gate conscious access. 2021 Cell Reports – Article.
- Alejandra Mondino… George Mashour, Giancarlo Vanini. Glutamatergic neurons in the preoptic hypothalamus promote wakefulness, destabilize NREM sleep, suppress REM sleep, and regulate cortical dynamics. 2021, Journal of Neuroscience – Article.
- George Mashour, Pietr Roelfsema, Jean-Pierre Changeux, Stanislas Dehaene. Conscious processing and the global neuronal workspace hypothesis. 2020, Neuron – Review.