William Stacey, M.D., Ph.D.

Michigan Neuroscience Institute Affiliate
Professor of Neurology
Professor of Biomedical Engineering

Neurology, Biomedical Engineering

B10-A187, NCRC

2800 Plymouth

Ann Arbor, MI 48109-2800


Dr. Stacey received both his medical degree and his PhD in Biomedical Engineering from Case Western Reserve University in Cleveland. He completed a Neurology residency at University Hospitals of Cleveland, then went to the University of Pennsylvania, to complete a clinical fellowship in Epilepsy. While there, he completed a post-doctorate in basic epilepsy research and also received a Master's of Translational Medicine. Dr. Stacey's clinical and research interests are integrally connected: he cares for adult patients with epilepsy and has an active research lab researching methods to understand and control seizures with implantable devices. The lab uses a combination of electrophysiology, machine learning, signal processing, and computational modeling. Data for these projects are acquired from a large, growing database of human patients and from rodent models of epilepsy. The lab is specifically researching the relationship of high frequency oscillations with seizure mechanisms, and developing methods to target and stimulate the brain to stop seizures. Concurrently, the lab is developing biophysical and dynamical models of epileptic activity to understand the mechanisms underlying seizures and epileptic oscillations.

Areas of Interest

EEG, epilepsy and intraoperative monitoring programs and developing a research program focused on understanding mechanisms underlying the basic physiological generators of epileptic seizures and translating this work into novel device therapies to stop seizures.

Clinical Interests



Medical School or Training

  • Case Western Reserve University School of Medicine, 2002


  • University Hospitals - Case Medical Center, Neurology, OH, 2006


  • Epilepsy, University of Pennsylvania Hospital, 2008

Board Certification

  • Neurology
  • Epilepsy

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