UM SBDRC Publications

Research Acknowledgement

Our productivity and effectiveness as a center are measured in part by the citation of the grant in published work. It is extremely important that our grant is cited in all publications resulting from the use of UM-SBDRC services and funding. Please use the following acknowledgement in your publications:

"This work utilized Core Services and Pilot or Feasibility project funding supported by grant UM-SBDRC 1P30AR075043 of NIH/NIAMS to the University of Michigan."

 

PUBLICATIONS TO DATE

(6/1/2019-2/27/24)

  1. Somadder R, Faraj L, Datta S, Kanapathipillai M, Ghosh G. Effect of extracellular matrices on production and potency of mesenchymal stem cell-derived exosomes. Biotechnol J. 2024 Feb;19(2):e2300474. doi: 10.1002/biot.202300474. PubMed PMID: 38403471.
  2. Uppala R, Sarkar MK, Young KZ, Ma F, Vemulapalli P, Wasikowski R, Plazyo O, Swindell WR, Maverakis E, Gharaee-Kermani M, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE. HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling. iScience. 2024 Feb 16;27(2):108986. doi: 10.1016/j.isci.2024.108986. eCollection 2024 Feb 16. PubMed PMID: 38327798; PubMed Central PMCID: PMC10847730.
  3. Shoffner-Beck SK, Abernathy-Close L, Lazar S, Ma F, Gharaee-Kermani M, Hurst A, Dobry C, Pandian D, Wasikowski R, Victory A, Arnold K, Gudjonsson JE, Tsoi LC, Kahlenberg JM. Lupus dermal fibroblasts are pro-inflammatory and exhibit a pro-fibrotic phenotype in scarring skin disease. JCI Insight. 2024 Feb 15:e173437. doi: 10.1172/jci.insight.173437. Epub ahead of print. PMID: 38358820.
  4. Petrova E, López-Gay JM, Fahrner M, Leturcq F, de Villartay JP, Barbieux C, Gonschorek P, Tsoi LC, Gudjonsson JE, Schilling O, Hovnanian A. Comparative analyses of Netherton syndrome patients and Spink5 conditional knock-out mice uncover disease-relevant pathways. Commun Biol. 2024 Feb 5;7(1):152. doi:10.1038/s42003-024-05780-y. PMID: 38316920; PMCID: PMC10844249.
  5. van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa. J Clin Invest. 2024 Feb 1;134(3). doi: 10.1172/JCI169225. PubMed PMID: 38051587; PubMed Central PMCID: PMC10836805.
  6. Klein B, Reynolds MB, Xu B, Gharaee-Kermani M, Gao Y, Berthier CC, Henning S, Loftus SN, McNeely KE, Victory AM, Dobry C, Hile GA, Ma F, Turnier JL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM. Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity. bioRxiv. 2024 Jan 26;. doi: 10.1101/2024.01.23.576771. PubMed PMID: 38328232; PubMed Central PMCID: PMC10849619.
  7. Hwang A, Kechter J, Do T, Hughes A, Zhang N, Li X, Wasikowski R, Brumfiel C, Patel M, Boudreaux B, Bhullar P, Nassir S, Yousif M, DiCaudo DJ, Fox J, Gharaee-Kermani M, Xing X, Zunich S, Branch E, Kahlenberg JM, Billi AC, Plazyo O, Tsoi LC, Pittelkow MR, Gudjonsson JE, Mangold AR. Oral Baricitinib in the Treatment of Cutaneous Lichen Planus. medRxiv [Preprint]. 2024 Jan 11:2024.01.09.24300946. doi: 10.1101/2024.01.09.24300946. PMID: 38260663; PMCID: PMC10802654.
  8. Li Q, Patrick MT, Sreeskandarajan S, Kang J, Kahlenberg JM, Gudjonsson JE, He Z, Tsoi LC. Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors. Front Immunol. 2024 Jan 8;14:1309549. doi: 10.3389/fimmu.2023.1309549. PMID: 38259463; PMCID: PMC10800546.
  9. Cohen E, Johnson CN, Wasikowski R, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE, Coulombe PA. Significance of stress keratin expression in normal and diseased epithelia. iScience. 2024 Jan 5;27(2):108805. doi:10.1016/j.isci.2024.108805. PMID: 38299111; PMCID: PMC10828818.
  10. Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. PubMed PMID: 38172207; PubMed Central PMCID: PMC10764940.
  11. Ma F, Gharaee-Kermani M, Tsoi LC, Plazyo O, Chaskar P, Harms P, Patrick MT, Xing X, Hile G, Piketty C, Lazzari A, Van Delm W, Maverakis E, Nakamura M, Modlin RL, Kahlenberg JM, Billi AC, Julia V, Krishnaswamy JK, Gudjonsson JE. Single-cell profiling of prurigo nodularis demonstrates immune- stromal crosstalk driving profibrotic responses and reversal with nemolizumab. J Allergy Clin Immunol. 2024 Jan;153(1):146-160. doi: 10.1016/j.jaci.2023.07.005. Epub 2023 Jul 26. PubMed PMID: 37506977.
  12. Patrick MT, Sreeskandarajan S, Shefler A, Wasikowski R, Sarkar MK, Chen J, Qin T, Billi AC, Kahlenberg JM, Prens E, Hovnanian A, Weidinger S, Elder JT, Kuo CC, Gudjonsson JE, Tsoi LC. Large- scale functional inference for skin-expressing lncRNAs using expression and sequence information. JCI Insight. 2023 Dec 22;8(24). doi: 10.1172/jci.insight.172956. PubMed PMID: 38131377; PubMed Central PMCID: PMC10807743.
  13. Dand N, Stuart PE, Bowes J, Ellinghaus D, Nititham J, Saklatvala JR, Teder-Laving M, Thomas LF, Traks T, Uebe S, Assmann G, Baudry D, Behrens F, Billi AC, Brown MA, Burkhardt H, Capon F, Chung R, Curtis CJ, Duckworth M, Ellinghaus E, FitzGerald O, Gerdes S, Griffiths CEM, Gulliver S, Helliwell P, Ho P, Hoffmann P, Holmen OL, Huang ZM, Hveem K, Jadon D, Köhm M, Kraus C, Lamacchia C, Lee SH, Ma F, Mahil SK, McHugh N, McManus R, Modalsli EH, Nissen MJ, Nöthen M, Oji V, Oksenberg JR, Patrick MT, Perez-White BE, Ramming A, Rech J, Rosen C, Sarkar MK, Schett G, Schmidt B, Tejasvi T, Traupe H, Voorhees JJ, Wacker EM, Warren RB, Wasikowski R, Weidinger S, Wen X, Zhang Z, Barton A, Chandran V, Esko T, Foerster J, Franke A, Gladman DD, Gudjonsson JE, Gulliver W, Hüffmeier U, Kingo K, Kõks S, Liao W, Løset M, Mägi R, Nair RP, Rahman P, Reis A, Smith CH, Di Meglio P, Barker JN, Tsoi LC, Simpson MA, Elder JT. GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets. medRxiv. 2023 Oct 5;. doi: 10.1101/2023.10.04.23296543. PubMed PMID: 37873414; PubMed Central PMCID: PMC10593001.
  14. Cushing K, Gudjonsson JE, Speliotes E, Higgins PDR. An Assessment of Comparative Medication Durability in Inflammatory Bowel Disease Patients With and Without Co-morbid Psoriasis, Rheumatoid Arthritis, and/or Enteropathic Arthritis. Dig Dis Sci. 2023 Oct;68(10):4001-4008. doi: 10.1007/s10620- 023-08062-5. Epub 2023 Aug 9. PubMed PMID: 37555882; NIHMSID:NIHMS1965265.
  15. Veniaminova NA, Jia YY, Hartigan AM, Huyge TJ, Tsai SY, Grachtchouk M, Nakagawa S, Dlugosz AA, Atwood SX, Wong SY. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury. Cell Rep. 2023 Sep 26;42(9):113121. doi: 10.1016/j.celrep.2023.113121. Epub 2023 Sep 19. PubMed PMID: 37715952; PubMed Central PMCID: PMC10591672.
  16. Zaver SA, Sarkar MK, Egolf S, Zou J, Tiwaa A, Capell BC, Gudjonsson JE, Simpson CL. Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease. JCI Insight. 2023 Sep 22;8(18). doi: 10.1172/jci.insight.170739. PubMed PMID: 37561594; PubMed Central PMCID: PMC10561730.
  17. Davis FM, Melvin WJ, Mangum K, Tsoi LC, Joshi AD, Cai Q, Henke PK, Gudjonsson JE, Gallagher KA. The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase-Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development. Ann Surg. 2023 Sep 1;278(3):426-440. doi: 10.1097/SLA.0000000000005963. Epub 2023 Jun 16. PubMed PMID: 37325923; PubMed Central PMCID: PMC10526639.
  18. Fisher GJ, Wang B, Cui Y, Shi M, Zhao Y, Quan T, Voorhees JJ. Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes. J Cell Commun Signal. 2023 Sep;17(3):523-529. doi: 10.1007/s12079-023- 00743-0. Epub 2023 Apr 17. Review. PubMed PMID: 37067763; PubMed Central PMCID: PMC10409944.
  19. Quan T, Xia W, He T, Calderone K, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. Matrix Metalloproteinase-1 Expression in Fibroblasts Accelerates Dermal Aging and Promotes Papilloma Development in Mouse Skin. J Invest Dermatol. 2023 Sep;143(9):1700-1707.e1. doi: 10.1016/j.jid.2023.02.028. Epub 2023 Mar 11. PubMed PMID: 36914001.
  20. Billi AC, Wasikowski R, Ma F, Yalavarthi S, Hoy CK, Zuo Y, Patrick MT, Shah N, Parker C, Aaronson C, Harbaugh A, Lucido MF, Shedden K, Rao K, IglayReger HB, Burant CF, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Knight JS, Kanthi Y. Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia. JCI Insight. 2023 Aug 22;8(16). doi: 10.1172/jci.insight.166110. PubMed PMID: 37606044; PubMed Central PMCID: PMC10543737.
  21. Xing E, Ma F, Wasikowski R, Billi AC, Gharaee-Kermani M, Fox J, Dobry C, Victory A, Sarkar MK, Xing X, Plazyo O, Chen HW, Barber G, Jacobe H, Tsou PS, Modlin RL, Varga J, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Khanna D. Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis. JCI Insight. 2023 Aug 22;8(16). doi: 10.1172/jci.insight.171307. PubMed PMID: 37471168; PubMed Central PMCID: PMC10543736.
  22. Roth-Carter QR, Burks HE, Ren Z, Koetsier JL, Tsoi LC, Harms PW, Xing X, Kirma J, Harmon RM, Godsel LM, Perl AL, Gudjonsson JE, Green KJ. Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis. JCI Insight. 2023 Aug 22;8(16). doi: 10.1172/jci.insight.168955. PubMed PMID: 37471166; PubMed Central PMCID: PMC10543711.
  23. Young KZ, Sarkar MK, Gudjonsson JE. Pathophysiology of generalized pustular psoriasis. Exp Dermatol. 2023 Aug;32(8):1194-1203. doi: 10.1111/exd.14768. Epub 2023 Feb 20. Review. PubMed PMID: 36779688; PubMed Central PMCID: PMC10423307.
  24. Patrick MT, Nair RP, He K, Stuart PE, Billi AC, Zhou X, Gudjonsson JE, Oksenberg JR, Elder JT, Tsoi LC. Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling. Ann Neurol. 2023 Aug;94(2):384-397. doi: 10.1002/ana.26672. Epub 2023 May 18. PubMed PMID: 37127916; PubMed Central PMCID: PMC10524664.
  25. Ponde NO, Shoger KE, Khatun MS, Sarkar MK, Dey I, Taylor TC, Cisney RN, Arunkumar SP, Gudjonsson JE, Kolls JK, Gottschalk RA, Gaffen SL. SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor. J Immunol. 2023 Jul 15;211(2):252-260. doi: 10.4049/jimmunol.2300110. PubMed PMID: 37265402; PubMed Central PMCID: PMC10330444.
  26. Hile GA, Coit P, Xu B, Victory AM, Gharaee-Kermani M, Estadt SN, Maz MP, Martens JWS, Wasikowski R, Dobry C, Tsoi LC, Iglesias-Bartolome R, Berthier CC, Billi AC, Gudjonsson JE, Sawalha AH, Kahlenberg JM. Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin. Arthritis Rheumatol. 2023 Jul;75(7):1216-1228. doi: 10.1002/art.42460. Epub 2023 Apr 18. PubMed PMID: 36704840; PubMed Central PMCID: PMC10313771.
  27. Fries A, Saidoune F, Kuonen F, Dupanloup I, Fournier N, Guerra de Souza AC, Haniffa M, Ma F, Gudjonsson JE, Roesner L, Li Y, Werfel T, Conrad C, Gottardo R, Modlin RL, Di Domizio J, Gilliet M. Differentiation of IL-26(+) T(H)17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis. Nat Commun. 2023 Jun 30;14(1):3878. doi: 10.1038/s41467-023-39484-4. PubMed PMID: 37391412; PubMed Central PMCID: PMC10313793.
  28. Ma F, Plazyo O, Billi AC, Tsoi LC, Xing X, Wasikowski R, Gharaee-Kermani M, Hile G, Jiang Y, Harms PW, Xing E, Kirma J, Xi J, Hsu JE, Sarkar MK, Chung Y, Di Domizio J, Gilliet M, Ward NL, Maverakis E, Klechevsky E, Voorhees JJ, Elder JT, Lee JH, Kahlenberg JM, Pellegrini M, Modlin RL, Gudjonsson JE. Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis. Nat Commun. 2023 Jun 12;14(1):3455. doi:10.1038/s41467-023-39020-4. PubMed PMID: 37308489; PubMed Central PMCID: PMC10261041.
  29. Castillo RL, Sidhu I, Dolgalev I, Chu T, Prystupa A, Subudhi I, Yan D, Konieczny P, Hsieh B, Haberman RH, Selvaraj S, Shiomi T, Medina R, Girija PV, Heguy A, Loomis CA, Chiriboga L, Ritchlin C, Garcia-Hernandez ML, Carucci J, Meehan SA, Neimann AL, Gudjonsson JE, Scher JU, Naik S. Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems. Sci Immunol. 2023 Jun 8;8(84):eabq7991. doi: 10.1126/sciimmunol.abq7991. Epub 2023 Jun 2. PubMed PMID: 37267384; PubMed Central PMCID: PMC10502701.
  30. Loftus SN, Liu J, Berthier CC, Gudjonsson JE, Gharaee-Kermani M, Tsoi LC, Kahlenberg JM. Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model. Front Immunol. 2023;14:1162799. doi: 10.3389/fimmu.2023.1162799. eCollection 2023. PubMed PMID: 37261358; PubMed Central PMCID: PMC10227599.
  31. Veniaminova NA, Jia Y, Hartigan AM, Huyge TJ, Tsai SY, Grachtchouk M, Nakagawa S, Dlugosz AA, Atwood SX, Wong SY. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury. bioRxiv. 2023 May 5;. doi: 10.1101/2023.05.05.539454. PubMed PMID: 37205445; PubMed Central PMCID: PMC10187279.
  32. Hesson AM, Langen ES, Plazyo O, Gudjonsson JE, Ganesh SK. Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension. BMC Med Genomics. 2023 May 2;16(1):91. doi: 10.1186/s12920-023-01522-x. PubMed PMID: 37131171; PubMed Central PMCID: PMC10152005.
  33. Schuler CF 4th, Billi AC, Maverakis E, Tsoi LC, Gudjonsson JE. Novel insights into atopic dermatitis. J Allergy Clin Immunol. 2023 May;151(5):1145-1154. doi: 10.1016/j.jaci.2022.10.023. Epub 2022 Nov 22. Review. PubMed PMID: 36428114; PubMed Central PMCID: PMC10164702.
  34. Sarkar MK, Uppala R, Zeng C, Billi AC, Tsoi LC, Kidder A, Xing X, Perez White BE, Shao S, Plazyo O, Sirobhushanam S, Xing E, Jiang Y, Gallagher KA, Voorhees JJ, Kahlenberg JM, Gudjonsson JE. Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction. J Clin Invest. 2023 May 1;133(9). doi: 10.1172/JCI159393. PubMed PMID: 36928117; PubMed Central PMCID: PMC10145927.
  35. Shi B, Tsou PS, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. Senescent Cells Accumulate in Systemic Sclerosis Skin. J Invest Dermatol. 2023 Apr;143(4):661-664.e5. doi: 10.1016/j.jid.2022.09.652. Epub 2022 Sep 30. PubMed PMID: 36191640; PubMed Central PMCID: PMC10038878.
  36. Ke F, Benet ZL, Maz MP, Liu J, Dent AL, Kahlenberg JM, Grigorova IL. Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells. Elife. 2023 Mar 2;12. doi: 10.7554/eLife.83908. PubMed PMID: 36862132; PubMed Central PMCID: PMC9981149.
  37. Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, Perez White BE, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis. J Invest Dermatol. 2023 Feb;143(2):284-293. doi: 10.1016/j.jid.2022.08.052. Epub 2022 Sep 15. PubMed PMID: 36116512; PubMed Central PMCID: PMC10097410.
  38. Wiedemann J, Billi AC, Bocci F, Kashgari G, Xing E, Tsoi LC, Meller L, Swindell WR, Wasikowski R, Xing X, Ma F, Gharaee-Kermani M, Kahlenberg JM, Harms PW, Maverakis E, Nie Q, Gudjonsson JE, Andersen B. Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin. Cell Rep. 2023 Jan 31;42(1):111994. doi: 10.1016/j.celrep.2023.111994. Epub 2023 Jan 24. PubMed PMID: 36732947; PubMed Central PMCID: PMC9939370.
  39. Zhou JY, Sarkar MK, Okamura K, Harris JE, Gudjonsson JE, Fitzgerald KA. Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT). Proc Natl Acad Sci U S A. 2023 Jan 31;120(5):e2213777120. doi: 10.1073/pnas.2213777120. Epub 2023 Jan 24. PubMed PMID: 36693106; PubMed Central PMCID: PMC9945980.
  40. Ernst MK, Evans ST, Techner JM, Rothbaum RM, Christensen LF, Onay UV, Biyashev D, Demczuk MM, Nguyen CV, Honda KS, McCormick TS, Tsoi LC, Gudjonsson JE, Cooper KD, Lu KQ. Vitamin D3 and deconvoluting a rash. JCI Insight. 2023 Jan 24;8(2). doi: 10.1172/jci.insight.163789. PubMed PMID: 36692020; PubMed Central PMCID: PMC9977299.
  41. Drake RS, Villanueva MA, Vilme M, Russo DD, Navia A, Love JC, Shalek AK. Profiling Transcriptional Heterogeneity with Seq-Well S(3): A Low-Cost, Portable, High-Fidelity Platform for Massively Parallel Single-Cell RNA-Seq. Methods Mol Biol. 2023;2584:57-104. doi: 10.1007/978-1-0716-2756-3_3. PubMed PMID: 36495445.
  42. Mehta BK, Espinoza ME, Franks JM, Yuan Y, Wang Y, Wood T, Gudjonsson JE, Spino C, Fox DA, Khanna D, Whitfield ML. Machine-learning classification identifies patients with early systemic sclerosis as abatacept responders via CD28 pathway modulation. JCI Insight. 2022 Dec 22;7(24). doi: 10.1172/jci.insight.155282. PubMed PMID: 36355434; PubMed Central PMCID: PMC9869963.
  43. Schuler CF 4th, Gudjonsson JE. IL-33 antagonism does not improve chronic atopic dermatitis: What can we learn?. J Allergy Clin Immunol. 2022 Dec;150(6):1410-1411. doi: 10.1016/j.jaci.2022.10.009. Epub 2022 Oct 18. PubMed PMID: 36270492; PubMed Central PMCID: PMC10087095.
  44. Plazyo O, Gudjonsson JE. Hitting the Bullseye in Autoimmunity: Targeting Biologics through Tethering: Examining a Therapeutic Potential for Vitiligo and Beyond. J Invest Dermatol. 2022 Dec;142(12):3133- 3135. doi: 10.1016/j.jid.2022.07.005. Epub 2022 Aug 26. PubMed PMID: 36038402.
  45. Patrick MT, Li Q, Wasikowski R, Mehta N, Gudjonsson JE, Elder JT, Zhou X, Tsoi LC. Shared genetic risk factors and causal association between psoriasis and coronary artery disease. Nat Commun. 2022 Nov 2;13(1):6565. doi: 10.1038/s41467-022-34323-4. PubMed PMID: 36323703; PubMed Central PMCID: PMC9630428.
  46. Cushing KC, Du X, Chen Y, Stetson LC, Kuppa A, Chen VL, Kahlenberg JM, Gudjonsson JE, Vanderwerff B, Higgins PDR, Speliotes EK. Inflammatory Bowel Disease Risk Variants Are Associated with an Increased Risk of Skin Cancer. Inflamm Bowel Dis. 2022 Nov 2;28(11):1667-1676. doi: 10.1093/ibd/izab336. PubMed PMID: 35018451; PubMed Central PMCID: PMC9924040.
  47. Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi B, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair. Cell Mol Immunol. 2022 Nov;19(11):1251-1262. doi: 10.1038/s41423-022-00919-5. Epub 2022 Sep 20. PubMed PMID: 36127466; PubMed Central PMCID: PMC9622909.
  48. Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD. Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy. JCI Insight. 2022 Oct 24;7(20). doi: 10.1172/jci.insight.165502. PubMed PMID: 36278491; PubMed Central PMCID: PMC9744256.
  49. Goepfert A, Barske C, Lehmann S, Wirth E, Willemsen J, Gudjonsson JE, Ward NL, Sarkar MK, Hemmig R, Kolbinger F, Rondeau JM. IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling. Cell Rep. 2022 Oct 18;41(3):111489. doi: 10.1016/j.celrep.2022.111489. PubMed PMID: 36260993; PubMed Central PMCID: PMC9637376.
  50. Maverakis E, Liakos W, Park D, Patel F, Siddiqui F, Kailemia MJ, Ruhaak LR, Marusina AI, Luxardi G, Gudjonsson JE, Le ST, Armstrong AW, Liao W, Merleev AA, Lebrilla CB. The Psoriasis Glycome: Differential Expression of Cholesterol Particle Glycans and IgA Glycans Linked to Disease Severity. J Invest Dermatol. 2022 Oct;142(10):2817-2820.e7. doi: 10.1016/j.jid.2022.03.030. Epub 2022 Apr 22. PubMed PMID: 35469905.
  51. Khanna D, Padilla C, Tsoi LC, Nagaraja V, Khanna PP, Tabib T, Kahlenberg JM, Young A, Huang S, Gudjonsson JE, Fox DA, Lafyatis R. Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial. JCI Insight. 2022 Sep 8;7(17). doi: 10.1172/jci.insight.159566. PubMed PMID: 35943798; PubMed Central PMCID: PMC9536259.
  52. Davis FM, Tsoi LC, Ma F, Wasikowski R, Moore BB, Kunkel SL, Gudjonsson JE, Gallagher KA. Single- cell Transcriptomics Reveals Dynamic Role of Smooth Muscle Cells and Enrichment of Immune Cell Subsets in Human Abdominal Aortic Aneurysms. Ann Surg. 2022 Sep 1;276(3):511-521. doi: 10.1097/SLA.0000000000005551. Epub 2022 Jun 28. PubMed PMID: 35762613; PubMed Central PMCID: PMC9388616.
  53. Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E. Biogeographic and disease-specific alterations in epidermal lipid composition and single- cell analysis of acral keratinocytes. JCI Insight. 2022 Aug 22;7(16). doi: 10.1172/jci.insight.159762. PubMed PMID: 35900871; PubMed Central PMCID: PMC9462509.
  54. Merleev A, Ji-Xu A, Toussi A, Tsoi LC, Le ST, Luxardi G, Xing X, Wasikowski R, Liakos W, Brüggen MC, Elder JT, Adamopoulos IE, Izumiya Y, Leal AR, Li Q, Kuzminykh NY, Kirane A, Marusina AI, Gudjonsson JE, Maverakis E. Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G. JCI Insight. 2022 Aug 22;7(16). doi: 10.1172/jci.insight.141193. PubMed PMID: 35862195; PubMed Central PMCID: PMC9462487.
  55. Patrick MT, Bardhi R, Zhou W, Elder JT, Gudjonsson JE, Tsoi LC. Enhanced rare disease mapping for phenome-wide genetic association in the UK Biobank. Genome Med. 2022 Aug 9;14(1):85. doi: 10.1186/s13073-022-01094-y. PubMed PMID: 35945607; PubMed Central PMCID: PMC9364550.
  56. Do TH, Ma F, Andrade PR, Teles R, de Andrade Silva BJ, Hu C, Espinoza A, Hsu JE, Cho CS, Kim M, Xi J, Xing X, Plazyo O, Tsoi LC, Cheng C, Kim J, Bryson BD, O'Neill AM, Colonna M, Gudjonsson JE, Klechevsky E, Lee JH, Gallo RL, Bloom BR, Pellegrini M, Modlin RL. TREM2 macrophages induced by human lipids drive inflammation in acne lesions. Sci Immunol. 2022 Jul 22;7(73):eabo2787. doi: 10.1126/sciimmunol.abo2787. Epub 2022 Jul 22. PubMed PMID: 35867799; PubMed Central PMCID: PMC9400695.
  57. Kim SJ, Bale S, Verma P, Wan Q, Ma F, Gudjonsson JE, Hazen SL, Harms PW, Tsou PS, Khanna D, Tsoi LC, Gupta N, Ho KJ, Varga J. Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation. iScience. 2022 Jul 15;25(7):104669. doi: 10.1016/j.isci.2022.104669. eCollection 2022 Jul 15. PubMed PMID: 35856022; PubMed Central PMCID: PMC9287188.
  58. Tsoi LC, Xing X, Xing E, Wasikowski R, Shao S, Zeng C, Plazyo O, Kirma J, Jiang Y, Billi AC, Sarkar MK, Turnier JL, Uppala R, Smith KM, Helfrich Y, Voorhees JJ, Maverakis E, Modlin RL, Kahlenberg JM, Scott VE, Gudjonsson JE. Noninvasive Tape-Stripping with High-Resolution RNA Profiling Effectively Captures a Preinflammatory State in Nonlesional Psoriatic Skin. J Invest Dermatol. 2022 Jun;142(6):1587-1596.e2. doi: 10.1016/j.jid.2021.09.038. Epub 2021 Nov 19. PubMed PMID: 34808239; PubMed Central PMCID: PMC9117571.
  59. Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. J Clin Invest. 2022 Jun 1;132(11). doi: 10.1172/JCI151827. PubMed PMID: 35439173; PubMed Central PMCID: PMC9151693.
  60. Wolf SJ, Audu CO, Joshi A, denDekker A, Melvin WJ, Davis FM, Xing X, Wasikowski R, Tsoi LC, Kunkel SL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM, Gallagher KA. IFN-κ is critical for normal wound repair and is decreased in diabetic wounds. JCI Insight. 2022 May 9;7(9). doi: 10.1172/jci.insight.152765. PubMed PMID: 35358091; PubMed Central PMCID: PMC9090246.
  61. Trieu KG, Tsai SY, Eberl M, Ju V, Ford NC, Doane OJ, Peterson JK, Veniaminova NA, Grachtchouk M, Harms PW, Swartling FJ, Dlugosz AA, Wong SY. Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease. Cell Rep. 2022 May 3;39(5):110779. doi: 10.1016/j.celrep.2022.110779. PubMed PMID: 35508126; PubMed Central PMCID: PMC9127636.
  62. Jamerson TA, Li Q, Sreeskandarajan S, Budunova IV, He Z, Kang J, Gudjonsson JE, Patrick MT, Tsoi LC. Roles Played by Stress-Induced Pathways in Driving Ethnic Heterogeneity for Inflammatory Skin Diseases. Front Immunol. 2022;13:845655. doi: 10.3389/fimmu.2022.845655. eCollection 2022. Review. PubMed PMID: 35572606; PubMed Central PMCID: PMC9095822.
  63. Billi AC, Ma F, Plazyo O, Gharaee-Kermani M, Wasikowski R, Hile GA, Xing X, Yee CM, Rizvi SM, Maz MP, Berthier CC, Wen F, Tsoi LC, Pellegrini M, Modlin RL, Gudjonsson JE, Kahlenberg JM. Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation. Sci Transl Med. 2022 Apr 27;14(642):eabn2263. doi: 10.1126/scitranslmed.abn2263. Epub 2022 Apr 27. PubMed PMID: 35476593; PubMed Central PMCID: PMC9169615.
  64. Shefler A, Patrick MT, Wasikowski R, Chen J, Sarkar MK, Gudjonsson JE, Tsoi LC. Skin-Expressing lncRNAs in Inflammatory Responses. Front Genet. 2022;13:835740. doi: 10.3389/fgene.2022.835740. eCollection 2022. Review. PubMed PMID: 35559048; PubMed Central PMCID: PMC9086234.
  65. Dunlap GS, Billi AC, Xing X, Ma F, Maz MP, Tsoi LC, Wasikowski R, Hodgin JB, Gudjonsson JE, Kahlenberg JM, Rao DA. Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney. JCI Insight. 2022 Apr 22;7(8). doi: 10.1172/jci.insight.156341. PubMed PMID: 35290245; PubMed Central PMCID: PMC9089784.
  66. Harms PW, Verhaegen ME, Hu K, Hrycaj SM, Chan MP, Liu CJ, Grachtchouk M, Patel RM, Udager AM, Dlugosz AA. Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors. Mod Pathol. 2022 Apr;35(4):506-514. doi: 10.1038/s41379-021-00928-Epub 2021 Sep 30. PubMed PMID: 34593967; PubMed Central PMCID: PMC8964828.
  67. Tsoi LC, Hacini-Rachinel F, Fogel P, Rousseau F, Xing X, Patrick MT, Billi AC, Berthier CC, Kahlenberg JM, Lazzari A, Wiegmann H, Ständer S, Piketty C, Julia V, Krishnaswamy JK, Gudjonsson JE. Transcriptomic characterization of prurigo nodularis and the therapeutic response to nemolizumab. J Allergy Clin Immunol. 2022 Apr;149(4):1329-1339. doi: 10.1016/j.jaci.2021.10.004. Epub 2021 Nov 29. PubMed PMID: 34857395; PubMed Central PMCID: PMC8995330.
  68. Verhaegen ME, Harms PW, Van Goor JJ, Arche J, Patrick MT, Wilbert D, Zabawa H, Grachtchouk M, Liu CJ, Hu K, Kelly MC, Chen P, Saunders TL, Weidinger S, Syu LJ, Runge JS, Gudjonsson JE, Wong SY, Brownell I, Cieslik M, Udager AM, Chinnaiyan AM, Tsoi LC, Dlugosz AA. Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice. J Clin Invest. 2022 Apr 1;132(7). doi: 10.1172/JCI152069. PubMed PMID: 35143422; PubMed Central PMCID: PMC8970662.
  69. van Straalen KR, Prens EP, Gudjonsson JE. Insights into hidradenitis suppurativa. J Allergy Clin Immunol. 2022 Apr;149(4):1150-1161. doi: 10.1016/j.jaci.2022.02.003. Epub 2022 Feb 19. PubMed PMID: 35189127.
  70. Prasov L, Bohnsack BL, El Husny AS, Tsoi LC, Guan B, Kahlenberg JM, Almeida E, Wang H, Cowen EW, De Jesus AA, Jani P, Billi AC, Moroi SE, Wasikowski R, Almeida I, Almeida LN, Kok F, Garnai SJ, Mian SI, Chen MY, Warner BM, Ferreira CR, Goldbach-Mansky R, Hur S, Brooks BP, Richards JE, Hufnagel RB, Gudjonsson JE. DDX58(RIG-I)-related disease is associated with tissue-specific interferon pathway activation. J Med Genet. 2022 Mar;59(3):294-304. doi: 10.1136/jmedgenet-2020-107447. Epub 2021 Jan 25. PubMed PMID: 33495304; PubMed Central PMCID: PMC8310534.
  71. Estadt SN, Maz MP, Musai J, Kahlenberg JM. Mechanisms of Photosensitivity in Autoimmunity. J Invest Dermatol. 2022 Mar;142(3 Pt B):849-856. doi: 10.1016/j.jid.2021.05.007. Epub 2021 Jun 22. Review. PubMed PMID: 34167786; PubMed Central PMCID: PMC8688579.
  72. Harms PW, Verhaegen ME, Vo JN, Tien JC, Pratt D, Su F, Dhanasekaran SM, Cao X, Mangelberger D, VanGoor J, Choi JE, Ma VT, Dlugosz AA, Chinnaiyan AM. Viral Status Predicts the Patterns of Genome Methylation and Decitabine Response in Merkel Cell Carcinoma. J Invest Dermatol. 2022 Mar;142(3 Pt A):641-652. doi: 10.1016/j.jid.2021.07.173. Epub 2021 Aug 30. PubMed PMID: 34474081; PubMed Central PMCID: PMC8860850.
  73. Gangwar RS, Gudjonsson JE, Ward NL. Mouse Models of Psoriasis: A Comprehensive Review. J Invest Dermatol. 2022 Mar;142(3 Pt B):884-897. doi: 10.1016/j.jid.2021.06.019. Epub 2021 Dec 23. Review. PubMed PMID: 34953514; PubMed Central PMCID: PMC10190156.
  74. Xing E, Billi AC, Gudjonsson JE. Sex Bias and Autoimmune Diseases. J Invest Dermatol. 2022 Mar;142(3 Pt B):857-866. doi: 10.1016/j.jid.2021.06.008. Epub 2021 Aug 3. Review. PubMed PMID: 34362556.
  75. O'Neill AM, Liggins MC, Seidman JS, Do TH, Li F, Cavagnero KJ, Dokoshi T, Cheng JY, Shafiq F, Hata TR, Gudjonsson JE, Modlin RL, Gallo RL. Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne. Sci Transl Med. 2022 Feb 16;14(632):eabh1478. doi: 10.1126/scitranslmed.abh1478. Epub 2022 Feb 16. PubMed PMID: 35171653; PubMed Central PMCID: PMC9885891.
  76. Tsoi LC, Patrick MT, Shuai S, Sarkar MK, Chi S, Ruffino B, Billi AC, Xing X, Uppala R, Zang C, Fullmer J, He Z, Maverakis E, Mehta NN, Perez White BE, Getsios S, Helfrich Y, Voorhees JJ, Kahlenberg JM, Weidinger S, Gudjonsson JE. Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents. J Allergy Clin Immunol. 2022 Feb;149(2):640-649.e5. doi: 10.1016/j.jaci.2021.07.024. Epub 2021 Jul 31. PubMed PMID: 34343561; PubMed Central PMCID: PMC9451046.
  77. Godsel LM, Roth-Carter QR, Koetsier JL, Tsoi LC, Huffine AL, Broussard JA, Fitz GN, Lloyd SM, Kweon J, Burks HE, Hegazy M, Amagai S, Harms PW, Xing X, Kirma J, Johnson JL, Urciuoli G, Doglio LT, Swindell WR, Awatramani R, Sprecher E, Bao X, Cohen-Barak E, Missero C, Gudjonsson JE, Green KJ. Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor. J Clin Invest. 2022 Feb 1;132(3). doi: 10.1172/JCI144363. PubMed PMID: 34905516; PubMed Central PMCID: PMC8803337.
  78. Gharaee-Kermani M, Estadt SN, Tsoi LC, Wolf-Fortune SJ, Liu J, Xing X, Theros J, Reed TJ, Lowe L, Gruszka D, Ward NL, Gudjonsson JE, Kahlenberg JM. IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation. J Invest Dermatol. 2022 Jan;142(1):155-165.e3. doi: 10.1016/j.jid.2021.05.029. Epub 2021 Aug 5. PubMed PMID: 34364883; PubMed Central PMCID: PMC8688309.
  79. Gravemeyer J, Spassova I, Verhaegen ME, Dlugosz AA, Hoffmann D, Lange A, Becker JC. DNA- methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma. Oncogene. 2022 Jan;41(1):37-45. doi: 10.1038/s41388-021-02064-1. Epub 2021 Oct 19. PubMed PMID: 34667274; PubMed Central PMCID: PMC8724008.
  80. Shao S, Billi AC, Gudjonsson JE. Dynamic manifestation of autoimmune diseases in skin-cytokine hubs and paradoxic reactions. J Allergy Clin Immunol. 2022 Jan;149(1):45-47. doi: 10.1016/j.jaci.2021.11.014. Epub 2021 Nov 24. PubMed PMID: 34838585.
  81. Abernathy-Close L, Lazar S, Stannard J, Tsoi LC, Eddy S, Rizvi SM, Yee CM, Myers EM, Namas R, Lowe L, Reed TJ, Wen F, Gudjonsson JE, Kahlenberg JM, Berthier CC. B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity. Front Immunol. 2021;12:775353. doi: 10.3389/fimmu.2021.775353. eCollection 2021. PubMed PMID: 34868043; PubMed Central PMCID: PMC8640489.
  82. Shao S, Chen J, Swindell WR, Tsoi LC, Xing X, Ma F, Uppala R, Sarkar MK, Plazyo O, Billi AC, Wasikowski R, Smith KM, Honore P, Scott VE, Maverakis E, Kahlenberg JM, Wang G, Ward NL, Harms PW, Gudjonsson JE. Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris. JCI Insight. 2021 Oct 22;6(20). doi: 10.1172/jci.insight.151911. PubMed PMID: 34491907; PubMed Central PMCID: PMC8564909.
  83. Yan D, Blauvelt A, Dey AK, Golpanian RS, Hwang ST, Mehta NN, Myers B, Shi ZR, Yosipovitch G, Bell S, Liao W. New Frontiers in Psoriatic Disease Research, Part II: Comorbidities and Targeted Therapies. J Invest Dermatol. 2021 Oct;141(10):2328-2337. doi: 10.1016/j.jid.2021.02.743. Epub 2021 Apr 19. Review. PubMed PMID: 33888321; PubMed Central PMCID: PMC8464483.
  84. Shao S, Tsoi LC, Swindell WR, Chen J, Uppala R, Billi AC, Xing X, Zeng C, Sarkar MK, Wasikowski R, Jiang Y, Kirma J, Sun J, Plazyo O, Wang G, Harms PW, Voorhees JJ, Ward NL, Ma F, Pellegrini M, Merleev A, Perez White BE, Modlin RL, Andersen B, Maverakis E, Weidinger S, Kahlenberg JM, Gudjonsson JE. IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses. J Invest Dermatol. 2021 Oct;141(10):2436-2448. doi: 10.1016/j.jid.2021.03.019. Epub 2021 Apr 15. PubMed PMID: 33864770; PubMed Central PMCID: PMC9423738.
  85. Yan D, Gudjonsson JE, Le S, Maverakis E, Plazyo O, Ritchlin C, Scher JU, Singh R, Ward NL, Bell S, Liao W. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. J Invest Dermatol. 2021 Sep;141(9):2112- 2122.e3. doi: 10.1016/j.jid.2021.02.764. Epub 2021 Jul 22. Review. PubMed PMID: 34303522; PubMed Central PMCID: PMC8384663.
  86. Grachtchouk M, Liu J, Hutchin ME, Harms PW, Thomas D, Wei L, Wang A, Cummings D, Lowe L, Garlick J, Sciubba J, Chinnaiyan AM, Verhaegen ME, Dlugosz AA. Constitutive Hedgehog/GLI2 signaling drives extracutaneous basaloid squamous cell carcinoma development and bone remodeling. Carcinogenesis. 2021 Aug 19;42(8):1100-1109. doi: 10.1093/carcin/bgab050. PubMed PMID: 34117865; PubMed Central PMCID: PMC8374060.
  87. Sirobhushanam S, Lazar S, Kahlenberg JM. Interferons in Systemic Lupus Erythematosus. Rheum Dis Clin North Am. 2021 Aug;47(3):297-315. doi: 10.1016/j.rdc.2021.04.001. Epub 2021 Jun 10. Review. PubMed PMID: 34215365; PubMed Central PMCID: PMC8254852.
  88. Zeng C, Tsoi LC, Gudjonsson JE. Dysregulated epigenetic modifications in psoriasis. Exp Dermatol. 2021 Aug;30(8):1156-1166. doi: 10.1111/exd.14332. Epub 2021 Apr 5. Review. PubMed PMID: 33756010.
  89. Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y, Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK. Obesity accelerates hair thinning by stem cell-centric converging mechanisms. Nature. 2021 Jul;595(7866):266-271. doi: 10.1038/s41586-021-03624-x. Epub 2021 Jun 23. PubMed PMID: 34163066; PubMed Central PMCID: PMC9600322.
  90. Ma F, Hughes TK, Teles RMB, Andrade PR, de Andrade Silva BJ, Plazyo O, Tsoi LC, Do T, Wadsworth MH 2nd, Oulee A, Ochoa MT, Sarno EN, Iruela-Arispe ML, Klechevsky E, Bryson B, Shalek AK, Bloom BR, Gudjonsson JE, Pellegrini M, Modlin RL. The cellular architecture of the antimicrobial response network in human leprosy granulomas. Nat Immunol. 2021 Jul;22(7):839-850. doi: 10.1038/s41590-021-00956-8. Epub 2021 Jun 24. PubMed PMID: 34168371; PubMed Central PMCID: PMC8579511.
  91. Patrick MT, Bardhi R, Raja K, He K, Tsoi LC. Advancement in predicting interactions between drugs used to treat psoriasis and its comorbidities by integrating molecular and clinical resources. J Am Med Inform Assoc. 2021 Jun 12;28(6):1159-1167. doi: 10.1093/jamia/ocaa335. PubMed PMID: 33544847; PubMed Central PMCID: PMC8200269.
  92. Davis FM, Tsoi LC, Melvin WJ, denDekker A, Wasikowski R, Joshi AD, Wolf S, Obi AT, Billi AC, Xing X, Audu C, Moore BB, Kunkel SL, Daugherty A, Lu HS, Gudjonsson JE, Gallagher KA. Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms. J Exp Med. 2021 Jun 7;218(6). doi: 10.1084/jem.20201839. PubMed PMID: 33779682; PubMed Central PMCID: PMC8008365.
  93. Patrick MT, Stuart PE, Zhang H, Zhao Q, Yin X, He K, Zhou XJ, Mehta NN, Voorhees JJ, Boehnke M, Gudjonsson JE, Nair RP, Handelman SK, Elder JT, Liu DJ, Tsoi LC. Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis. J Invest Dermatol. 2021 Jun;141(6):1493-1502. doi: 10.1016/j.jid.2020.11.025. Epub 2020 Dec 30. PubMed PMID: 33385400; PubMed Central PMCID: PMC8154633.
  94. Dunstan RW, Salte KM, Todorović V, Lowe M, Wetter JB, Harms PW, Burney RE, Scott VE, Smith KM, Rosenblum MD, Gudjonsson JE, Honore P. Histologic progression of acne inversa/hidradenitis suppurativa: Implications for future investigations and therapeutic intervention. Exp Dermatol. 2021 Jun;30(6):820-830. doi: 10.1111/exd.14273. Epub 2021 Jan 20. PubMed PMID: 33377546; PubMed Central PMCID: PMC8247901.
  95. Turnier JL, Pachman LM, Lowe L, Tsoi LC, Elhaj S, Menon R, Amoruso MC, Morgan GA, Gudjonsson JE, Berthier CC, Kahlenberg JM. Comparison of Lesional Juvenile Myositis and Lupus Skin Reveals Overlapping Yet Unique Disease Pathophysiology. Arthritis Rheumatol. 2021 Jun;73(6):1062-1072. doi: 10.1002/art.41615. Epub 2021 May 2. PubMed PMID: 33305541; PubMed Central PMCID: PMC8274390.
  96. Griffiths CEM, Armstrong AW, Gudjonsson JE, Barker JNWN. Psoriasis. Lancet. 2021 Apr 3;397(10281):1301-1315. doi: 10.1016/S0140-6736(20)32549-6. Review. PubMed PMID: 33812489.
  97. Quan T, Xiang Y, Liu Y, Qin Z, Yang Y, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging. J Invest Dermatol. 2021 Apr;141(4S):1007-1016. doi: 10.1016/j.jid.2020.07.019. Epub 2020 Aug 13. PubMed PMID: 32800875; PubMed Central PMCID: PMC7881053.
  98. Sule G, Abuaita BH, Steffes PA, Fernandes AT, Estes SK, Dobry C, Pandian D, Gudjonsson JE, Kahlenberg JM, O'Riordan MX, Knight JS. Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus. J Clin Invest. 2021 Apr 1;131(7). doi: 10.1172/JCI137866. PubMed PMID: 33561013; PubMed Central PMCID: PMC8011900.
  99. Patrick MT, Zhang H, Wasikowski R, Prens EP, Weidinger S, Gudjonsson JE, Elder JT, He K, Tsoi LC. Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies. J Allergy Clin Immunol. 2021 Mar;147(3):857-869.e7. doi: 10.1016/j.jaci.2021.01.006. Epub 2021 Jan 21. PubMed PMID: 33485957; PubMed Central PMCID: PMC7825803.
  100. Hile GA, Kahlenberg JM. Immunopathogenesis of skin injury in systemic lupus erythematosus. Curr Opin Rheumatol. 2021 Mar 1;33(2):173-180. doi: 10.1097/BOR.0000000000000770. Review. PubMed PMID: 33315653; PubMed Central PMCID: PMC8208233.
  101. Simpson CL, Tokito MK, Uppala R, Sarkar MK, Gudjonsson JE, Holzbaur ELF. NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation. Cell Rep. 2021 Feb 2;34(5):108689. doi: 10.1016/j.celrep.2021.108689. PubMed PMID: 33535046; PubMed Central PMCID: PMC7888979.
  102. Uppala R, Tsoi LC, Harms PW, Wang B, Billi AC, Maverakis E, Michelle Kahlenberg J, Ward NL, Gudjonsson JE. "Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis. Cell Mol Immunol. 2021 Feb;18(2):307-317. doi: 10.1038/s41423-020-0519-3. Epub 2020 Aug 19. Review. PubMed PMID: 32814870; PubMed Central PMCID: PMC8027616.
  103. Shi B, Wang W, Korman B, Kai L, Wang Q, Wei J, Bale S, Marangoni RG, Bhattacharyya S, Miller S, Xu D, Akbarpour M, Cheresh P, Proccissi D, Gursel D, Espindola-Netto JM, Chini CCS, de Oliveira GC, Gudjonsson JE, Chini EN, Varga J. Targeting CD38-dependent NAD(+) metabolism to mitigate multiple organ fibrosis. iScience. 2021 Jan 22;24(1):101902. doi: 10.1016/j.isci.2020.101902. eCollection 2021 Jan 22. PubMed PMID: 33385109; PubMed Central PMCID: PMC7770554.
  104. Kahlenberg JM. Rethinking the Pathogenesis of Cutaneous Lupus. J Invest Dermatol. 2021 Jan;141(1):32-35. doi: 10.1016/j.jid.2020.05.077. Epub 2020 Jun 27. Review. PubMed PMID: 32605817; PubMed Central PMCID: PMC7752835.
  105. Munger E, Choi H, Dey AK, Elnabawi YA, Groenendyk JW, Rodante J, Keel A, Aksentijevich M, Reddy AS, Khalil N, Argueta-Amaya J, Playford MP, Erb-Alvarez J, Tian X, Wu C, Gudjonsson JE, Tsoi LC, Jafri MS, Sandfort V, Chen MY, Shah SJ, Bluemke DA, Lockshin B, Hasan A, Gelfand JM, Mehta NN. Application of machine learning to determine top predictors of noncalcified coronary burden in psoriasis: An observational cohort study. J Am Acad Dermatol. 2020 Dec;83(6):1647-1653. doi: 10.1016/j.jaad.2019.10.060. Epub 2019 Oct 31. PubMed PMID: 31678339; PubMed Central PMCID: PMC7428853.
  106. Maz MP, Michelle Kahlenberg J. Cutaneous and systemic connections in lupus. Curr Opin Rheumatol. 2020 Nov;32(6):583-589. doi: 10.1097/BOR.0000000000000739. Review. PubMed PMID: 32826479; PubMed Central PMCID: PMC8000781.
  107. Richer J, Hill HL, Wang Y, Yang ML, Hunker KL, Lane J, Blackburn S, Coleman DM, Eliason J, Sillon G, D'Agostino MD, Jetty P, Mongeon FP, Laberge AM, Ryan SE, Fendrikova-Mahlay N, Coutinho T, Mathis MR, Zawistowski M, Hazen SL, Katz AE, Gornik HL, Brummett CM, Abecasis G, Bergin IL, Stanley JC, Li JZ, Ganesh SK. A Novel Recurrent COL5A1 Genetic Variant Is Associated With a Dysplasia-Associated Arterial Disease Exhibiting Dissections and Fibromuscular Dysplasia. Arterioscler Thromb Vasc Biol. 2020 Nov;40(11):2686-2699. doi: 10.1161/ATVBAHA.119.313885. Epub 2020 Sep 17.PubMed PMID: 32938213; PubMed Central PMCID: PMC7953329.
  108. Gudjonsson JE, Elder JT. Meeting Report: 68(th) Montagna Symposium on the Biology of Skin "Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology". J Invest Dermatol. 2020 Nov;140(11):2105-2110. doi: 10.1016/j.jid.2020.06.010. Epub 2020 Jun 27. PubMed PMID: 32603751; PubMed Central PMCID: PMC7606754.
  109. Jiang Y, Tsoi LC, Billi AC, Ward NL, Harms PW, Zeng C, Maverakis E, Kahlenberg JM, Gudjonsson JE. Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin. JCI Insight. 2020 Oct 15;5(20). doi: 10.1172/jci.insight.142067. Review. PubMed PMID: 33055429; PubMed Central PMCID: PMC7605526.
  110. Hughes TK, Wadsworth MH 2nd, Gierahn TM, Do T, Weiss D, Andrade PR, Ma F, de Andrade Silva BJ, Shao S, Tsoi LC, Ordovas-Montanes J, Gudjonsson JE, Modlin RL, Love JC, Shalek AK. Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. Immunity. 2020 Oct 13;53(4):878-894.e7. doi: 10.1016/j.immuni.2020.09.015. PubMed PMID: 33053333; PubMed Central PMCID: PMC7562821.
  111. Gudjonsson JE, Tsoi LC, Ma F, Billi AC, van Straalen KR, Vossen ARJV, van der Zee HH, Harms PW, Wasikowski R, Yee CM, Rizvi SM, Xing X, Xing E, Plazyo O, Zeng C, Patrick MT, Lowe MM, Burney RE, Kozlow JH, Cherry-Bukowiec JR, Jiang Y, Kirma J, Weidinger S, Cushing KC, Rosenblum MD, Berthier C, MacLeod AS, Voorhees JJ, Wen F, Kahlenberg JM, Maverakis E, Modlin RL, Prens EP. Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis. JCI Insight. 2020 Oct 2;5(19). doi: 10.1172/jci.insight.139930. PubMed PMID: 32853177; PubMed Central PMCID: PMC7566715.
  112. Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD. Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy. JCI Insight. 2020 Oct 2;5(19). doi: 10.1172/jci.insight.139932. PubMed PMID: 32841223; PubMed Central PMCID: PMC7566733.
  113. Davis FM, Tsoi LC, Wasikowski R, denDekker A, Joshi A, Wilke C, Deng H, Wolf S, Obi A, Huang S, Billi AC, Robinson S, Lipinski J, Melvin WJ, Audu CO, Weidinger S, Kunkel SL, Smith A, Gudjonsson JE, Moore BB, Gallagher KA. Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair. JCI Insight. 2020 Sep 3;5(17). doi: 10.1172/jci.insight.138443. PubMed PMID: 32879137; PubMed Central PMCID: PMC7526451.
  114. Baumer Y, Dey AK, Gutierrez-Huerta CA, Khalil NO, Sekine Y, Sanda GE, Zhuang J, Saxena A, Stempinski E, Elnabawi YA, Dagur PK, Ng Q, Teague HL, Keel A, Rodante JA, Boisvert WA, Tsoi LC, Gudjonsson JE, Bleck CKE, Chen MY, Bluemke DA, Gelfand JM, Schwartz DM, Kruth HS, Powell- Wiley TM, Playford MP, Mehta NN. Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis. EBioMedicine. 2020 Sep;59:102876. doi: 10.1016/j.ebiom.2020.102876. Epub 2020 Jul 6. PubMed PMID: 32646751; PubMed Central PMCID: PMC7502673.
  115. Tsoi LC, Gharaee-Kermani M, Berthier CC, Nault T, Hile GA, Estadt SN, Patrick MT, Wasikowski R, Billi AC, Lowe L, Reed TJ, Gudjonsson JE, Kahlenberg JM. IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions. JCI Insight. 2020 Aug 20;5(16). doi: 10.1172/jci.insight.139558. PubMed PMID: 32644977; PubMed Central PMCID: PMC7455118.
  116. Hile GA, Gudjonsson JE, Kahlenberg JM. The influence of interferon on healthy and diseased skin. Cytokine. 2020 Aug;132:154605. doi: 10.1016/j.cyto.2018.11.022. Epub 2018 Dec 6. Review. PubMed PMID: 30527631; PubMed Central PMCID: PMC6551332.
  117. Gudjonsson JE, Kabashima K, Eyerich K. Mechanisms of skin autoimmunity: Cellular and soluble immune components of the skin. J Allergy Clin Immunol. 2020 Jul;146(1):8-16. doi: 10.1016/j.jaci.2020.05.009. Review. PubMed PMID: 32631499.
  118. Billi AC, Ludwig JE, Fritz Y, Rozic R, Swindell WR, Tsoi LC, Gruzska D, Abdollahi-Roodsaz S, Xing X, Diaconu D, Uppala R, Camhi MI, Klenotic PA, Sarkar MK, Husni ME, Scher JU, McDonald C, Kahlenberg JM, Midura RJ, Gudjonsson JE, Ward NL. KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. J Clin Invest. 2020 Jun 1;130(6):3151-3157. doi: 10.1172/JCI133159. PubMed PMID: 32155135; PubMed Central PMCID: PMC7260032.
  119. Sirobhushanam S, Parsa N, Reed TJ, Berthier CC, Sarkar MK, Hile GA, Tsoi LC, Banfield J, Dobry C, Horswill AR, Gudjonsson JE, Kahlenberg JM. Staphylococcus aureus Colonization Is Increased on Lupus Skin Lesions and Is Promoted by IFN-Mediated Barrier Disruption. J Invest Dermatol. 2020 May;140(5):1066-1074.e4. doi: 10.1016/j.jid.2019.11.016. Epub 2019 Dec 23. PubMed PMID: 31877319; PubMed Central PMCID: PMC7183889.
  120. Tsoi LC, Rodriguez E, Stölzl D, Wehkamp U, Sun J, Gerdes S, Sarkar MK, Hübenthal M, Zeng C, Uppala R, Xing X, Thielking F, Billi AC, Swindell WR, Shefler A, Chen J, Patrick MT, Harms PW, Kahlenberg JM, Perez White BE, Maverakis E, Gudjonsson JE, Weidinger S. Progression of acute-to- chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses. J Allergy Clin Immunol. 2020 May;145(5):1406-1415. doi: 10.1016/j.jaci.2019.11.047. Epub 2019 Dec 28. PubMed PMID: 31891686; PubMed Central PMCID: PMC7214216.
  121. Hile G, Kahlenberg JM, Gudjonsson JE. Recent genetic advances in innate immunity of psoriatic arthritis. Clin Immunol. 2020 May;214:108405. doi: 10.1016/j.clim.2020.108405. Epub 2020 Apr 2. Review. PubMed PMID: 32247832.
  122. Shi H, Gudjonsson JE, Kahlenberg JM. Treatment of cutaneous lupus erythematosus: current approaches and future strategies. Curr Opin Rheumatol. 2020 May;32(3):208-214. doi: 10.1097/BOR.0000000000000704. Review. PubMed PMID: 32141953; PubMed Central PMCID: PMC7357847.
  123. Shao S, Wang G, Maverakis E, Gudjonsson JE. Targeted Treatment for Erythrodermic Psoriasis: Rationale and Recent Advances. Drugs. 2020 Apr;80(6):525-534. doi: 10.1007/s40265-020-01283-2. Review. PubMed PMID: 32180204; PubMed Central PMCID: PMC7167352.
  124. Kwock JT, Handfield C, Suwanpradid J, Hoang P, McFadden MJ, Labagnara KF, Floyd L, Shannon J, Uppala R, Sarkar MK, Gudjonsson JE, Corcoran DL, Lazear HM, Sempowski G, Horner SM, MacLeod AS. IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection. Sci Adv. 2020 Apr;6(14):eaay3245. doi: 10.1126/sciadv.aay3245. eCollection 2020 Apr. PubMed PMID: 32270034; PubMed Central PMCID: PMC7112749.
  125. Kahlenberg JM, Billi AC, Eyerich K, Gudjonsson JE. Biologics in the treatment of skin and rheumatologic diseases. J Allergy Clin Immunol. 2020 Apr;145(4):1138-1141. doi: 10.1016/j.jaci.2020.02.017. Epub 2020 Feb 27. Review. PubMed PMID: 32112793; PubMed Central PMCID: PMC8842991.
  126. Greenberg EN, Marshall ME, Jin S, Venkatesh S, Dragan M, Tsoi LC, Gudjonsson JE, Nie Q, Takahashi JS, Andersen B. Circadian control of interferon-sensitive gene expression in murine skin. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5761-5771. doi: 10.1073/pnas.1915773117. Epub 2020 Mar 4. PubMed PMID: 32132203; PubMed Central PMCID: PMC7084068.
  127. denDekker AD, Davis FM, Joshi AD, Wolf SJ, Allen R, Lipinski J, Nguyen B, Kirma J, Nycz D, Bermick J, Moore BB, Gudjonsson JE, Kunkel SL, Gallagher KA. TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF. JCI Insight. 2020 Mar 12;5(5). doi: 10.1172/jci.insight.132306. PubMed PMID: 32069267; PubMed Central PMCID: PMC7141388.
  128. Billi AC, Sarkar MK, Gudjonsson JE. When bugs and drugs conspire: driving acneiform skin toxicity. J Clin Invest. 2020 Mar 2;130(3):1090-1092. doi: 10.1172/JCI133787. PubMed PMID: 32015232; PubMed Central PMCID: PMC7269584.
  129. Shao S, Gudjonsson JE. Epigenetics of Psoriasis. Adv Exp Med Biol. 2020;1253:209-221. doi: 10.1007/978-981-15-3449-2_8. Review. PubMed PMID: 32445097.
  130. Zeng C, Kahlenberg JM, Gudjonsson JE. IL-17A Softens the Skin: Antifibrotic Properties of IL-17A in Systemic Sclerosis. J Invest Dermatol. 2020 Jan;140(1):13-14. doi: 10.1016/j.jid.2019.07.678. PubMed PMID: 31864428.
  131. Toussi A, Merleev A, Barton VR, Le ST, Marusina A, Luxardi G, Kirma J, Xing X, Adamopoulos IE, Fung MA, Raychaudhuri SP, Shimoda M, Gudjonsson JE, Maverakis E. Transcriptome mining and B cell depletion support a role for B cells in psoriasis pathophysiology. J Dermatol Sci. 2019 Dec;96(3):181-184. doi: 10.1016/j.jdermsci.2019.11.006. Epub 2019 Nov 19. PubMed PMID: 31780313.
  132. Billi AC, Gudjonsson JE, Voorhees JJ. Psoriasis: Past, Present, and Future. J Invest Dermatol. 2019 Nov;139(11):e133-e142. doi: 10.1016/j.jid.2019.08.437. Review. PubMed PMID: 31648690; PubMed Central PMCID: PMC6989032.
  133. Park JE, Yonet-Tanyeri N, Vander Ende E, Henry AI, Perez White BE, Mrksich M, Van Duyne RP. Plasmonic Microneedle Arrays for in Situ Sensing with Surface-Enhanced Raman Spectroscopy (SERS). Nano Lett. 2019 Oct 9;19(10):6862-6868. doi: 10.1021/acs.nanolett.9b02070. Epub 2019 Oct 1. PubMed PMID: 31545611; PubMed Central PMCID: PMC7398609.
  134. Shao S, Tsoi LC, Sarkar MK, Xing X, Xue K, Uppala R, Berthier CC, Zeng C, Patrick M, Billi AC, Fullmer J, Beamer MA, Perez-White B, Getsios S, Schuler A, Voorhees JJ, Choi S, Harms P, Kahlenberg JM, Gudjonsson JE. IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus. Sci Transl Med. 2019 Sep 25;11(511). doi: 10.1126/scitranslmed.aav7561. PubMed PMID: 31554739; PubMed Central PMCID: PMC7285657.
  135. Wolf SJ, Estadt SN, Theros J, Moore T, Ellis J, Liu J, Reed TJ, Jacob CO, Gudjonsson JE, Kahlenberg JM. Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells. J Autoimmun. 2019 Sep;103:102291. doi: 10.1016/j.jaut.2019.06.002. Epub 2019 Jun 24. PubMed PMID: 31248690; PubMed Central PMCID: PMC6708464.
  136. Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, Moore BB, Kunkel SL, Gallagher KA. The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. Immunity. 2019 Aug 20;51(2):258-271.e5. doi: 10.1016/j.immuni.2019.06.015. Epub 2019 Jul 23. PubMed PMID: 31350176; PubMed Central PMCID: PMC6703945.
  137. Berthier CC, Tsoi LC, Reed TJ, Stannard JN, Myers EM, Namas R, Xing X, Lazar S, Lowe L, Kretzler M, Gudjonsson JE, Kahlenberg JM. Molecular Profiling of Cutaneous Lupus Lesions Identifies Subgroups Distinct from Clinical Phenotypes. J Clin Med. 2019 Aug 17;8(8). doi: 10.3390/jcm8081244. PubMed PMID: 31426521; PubMed Central PMCID: PMC6723404.
  138. Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S. Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis. J Invest Dermatol. 2019 Jul;139(7):1480-1489. doi: 10.1016/j.jid.2018.12.018. Epub 2019 Jan 11. PubMed PMID: 30641038; PubMed Central PMCID: PMC6711380.
  139. Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE. The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. JCI Insight. 2019 Apr 18;4(8). doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18. PubMed PMID: 30996136; PubMed Central PMCID: PMC6538382.
  140. Patrick MT, Stuart PE, Raja K, Chi S, He Z, Voorhees JJ, Tejasvi T, Gudjonsson JE, Kahlenberg JM, Chandran V, Rahman P, Gladman DD, Nair RP, Elder JT, Tsoi LC. Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC. Front Genet. 2019;10:304. doi: 10.3389/fgene.2019.00304. eCollection 2019. PubMed PMID: 31031798; PubMed Central PMCID: PMC6470186.
  141. Le ST, Merleev AA, Luxardi G, Shimoda M, Adamopoulos IE, Tsoi LC, Wang JZ, Alexanian C, Raychaudhuri SP, Hwang ST, Gudjonsson J, Marusina AI, Maverakis E. 2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells. Front Immunol. 2019;10:589. doi: 10.3389/fimmu.2019.00589. eCollection 2019. PubMed PMID: 31019502; PubMed Central PMCID: PMC6458264.
  142. Tsoi LC, Hile GA, Berthier CC, Sarkar MK, Reed TJ, Liu J, Uppala R, Patrick M, Raja K, Xing X, Xing E, He K, Gudjonsson JE, Kahlenberg JM. Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus. J Immunol. 2019 Apr 1;202(7):2121-2130. doi: 10.4049/jimmunol.1800650. Epub 2019 Feb 11. PubMed PMID: 30745462; PubMed Central PMCID: PMC6424612.
  143. Patrick MT, Raja K, Miller K, Sotzen J, Gudjonsson JE, Elder JT, Tsoi LC. Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach. J Invest Dermatol. 2019 Mar;139(3):683-691. doi: 10.1016/j.jid.2018.09.018. Epub 2018 Oct 17. PubMed PMID: 30342048; PubMed Central PMCID: PMC6387843.
  144. Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, Baumer Y, Harrington CL, Stempinski E, Elnabawi YA, Dagur PK, Cui K, Tunc I, Seifuddin F, Joshi AA, Stansky E, Purmalek MM, Rodante JA, Keel A, Aridi TZ, Carmona-Rivera C, Sanda GE, Chen MY, Pirooznia M, McCoy JP Jr, Gelfand JM, Zhao K, Gudjonsson JE, Playford MP, Kaplan MJ, Berger JS, Mehta NN. Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis. JACC Basic Transl Sci. 2019 Feb;4(1):1-14. doi: 10.1016/j.jacbts.2018.10.008. eCollection 2019 Feb. PubMed PMID: 30847414; PubMed Central PMCID: PMC6390681.
  145. Billi AC, Kahlenberg JM, Gudjonsson JE. Sex bias in autoimmunity. Curr Opin Rheumatol. 2019 Jan;31(1):53-61. doi: 10.1097/BOR.0000000000000564. Review. PubMed PMID: 30394940; PubMed Central PMCID: PMC6296774.
  146. Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM. Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa. Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18. PubMed PMID: 30021804; PubMed Central PMCID: PMC6185784.
  147. Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL. IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a. Sci Signal. 2018 Oct 9;11(551). doi: 10.1126/scisignal.aat4617. PubMed PMID: 30301788; PubMed Central PMCID: PMC6188668.