Animal Modeling Core
The Animal Modeling Core will provide services to help researchers design and develop genetically engineered mouse models (GEMMs), including providing resources regarding GEMM production, breeding, screening, and validation; derivation of primary cell cultures; and establishment of cell lines from GEMMs & providing services regarding GEMM phenotyping and in vivo manipulation, including transgene induction, UV irradiation, inflammation, and fibrosis models
Functional Analytics Core
The Functional Analytics Core will provide unique, state-of-the art services for CRISPR/Cas9 mutagenesis in keratinocytes, with genomic profiling of genetically-altered keratinocytes, and integration into the systems biology pipeline for data analyses/interpretation, and direct access to bioinformatics analyses and large-scale genomic datasets through a web-based interface