Functional Analytics Core

The role of the Functional Analytics Core (FAC) is to accelerate, enhance, and enrich the effectiveness of ongoing basic and translational research, and to help bring outside investigators into the field of cutaneous biology.


We provide CRISPR/Cas9 genome editing services in keratinocytes for generation of both knock-out and knock-in keratinocytes, as well as functional characterization of mutant keratinocyte lines. In addition, we provide access to systems biology analyses, disease- and cytokine-specific gene expression profiling, and training.

The U-M SBDRC Skin Genes Query supports comparison of normal and disease gene expression in human and mouse skin utilizing datasets supplied by SBDRC members. This tool is available to all UM SBDRC members and requires University of Michigan level-1 account verification. If you are unable to access this tool and are a current UM SBDRC member, please email Carmel McKeon ([email protected]) for assistance.

If you are interested in the FAC bioinformatics services, please email .
If you are interested in the FAC cell line services, please email 


Dr. Johann Gudjonsson

Johann Gudjonsson, MD, PhD

Director, UM Skin Biology and Diseases Resource-based Center
Director, UM-SBDRC Administrative and Functional Analytics Cores

Dr. Lam (Alex) Tsoi

Lam (Alex) Tsoi, PhD

Associate Director, UM-SBDRC Functional Analytics Core