We provide CRISPR/Cas9 genome editing services in keratinocytes for generation of both knock-out and knock-in keratinocytes, as well as functional characterization of mutant keratinocyte lines. In addition, we provide access to systems biology analyses, disease- and cytokine-specific gene expression profiling, and training.
Services:
CRISPR/Cas9 Genome Editing
Skin Genes Query
The U-M SBDRC Skin Genes Query supports comparison of normal and disease gene expression in human and mouse skin utilizing datasets supplied by SBDRC members. This tool is available to all UM SBDRC members and requires University of Michigan level-1 account verification. If you are unable to access this tool and are a current UM SBDRC member, please email Carmel McKeon ([email protected]) for assistance.
Contact Us:
If you are interested in the FAC bioinformatics services, please email [email protected].
If you are interested in the FAC cell line services, please email [email protected].
Directors
Johann Gudjonsson, MD, PhD
Director, UM Skin Biology and Diseases Resource-based Center
Director, UM-SBDRC Administrative and Functional Analytics Cores
Lam (Alex) Tsoi, PhD
Associate Director, UM-SBDRC Functional Analytics Core