Dr. Neumar has over 20 years of research experience in the field of cardiac arrest resuscitation and traumatic brain injury. His basic science research has been focused on mechanisms of neuronal injury after ischemic and traumatic brain injury, as well as therapeutic strategies to improve neurologic outcomes including therapeutic hypothermia. More recently, his laboratory research focus has expanded to studies of ischemic post-conditioning in collaboration with Dr. Demetris Yannopoulos’ research team at the University of Minnesota and studies of extracorporeal cardiopulmonary resuscitation (ECPR) in collaboration with Dr. Robert Bartlett’s research team in the ECLS Research Laboratory at the University of Michigan. He is also collaborating to develop a novel extracorporeal cardiopulmonary resuscitation (ECPR) device designed to provide goal-directed reperfusion using an automated closed-loop monitoring and control system. A major focus of Dr. Neumar’s laboratory has been to elucidate the role of calpains in post-ischemic neuronal death and has also focused on optimizing post-cardiac arrest hypothermic targeted temperature management (HTTM). The major focus of his clinical research is optimizing the management of post-cardiac arrest syndrome.