Explore significant publications from the Translational Tumor Immunology Lab.

Key Publications

  1. Li Q., Lu L., Tao, H., Xue, C., Teitz-Tennenbaum, S., Owen, J., Moyer, J.S., Prince, M.E.P., Chang, A.E., Wicha, M.S.: Generation of a novel dendritic-cell vaccine using melanoma and squamous cancer stem cells. Journal of Visualized Experiments 83, 1-7, 2014.
  2. Huimin Tao, Lin Lu, Yang Xia, Fu Dai, Yi Wang, Yangyi Bao, Steven K. Lundy, Fumito Ito, Qin Pan, Xiaolian Zhang, Fang Zheng, Guoshun Shu, Bingmu Fang, Jinhong Jiang, Jianchuang Xia, Shiang Huang, Qiao Li and Alfred E. Chang: Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL-10. Eur. J. Immunol. 45: 999–1009, 2015.
  3. Lin Lu, Huimin Tao, Alfred E Chang, Yangyang Hu, Guoshun Shu, Quanning Chen, Martin Egenti, John Owen, Jeffrey S Moyer, Mark Ep Prince, Jian-chuan Xia, Shiang Huang, Max S Wicha, and Qiao Li: Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immuneresponses against cancer stem cells. OncoImmunology 4:3, e990767, 2015.
  4. Qin Pan, Qiao Li, Shuang Liu, Ning, XiaoLian Zheng, Yingxin Xu, Alfred E. Chang, Max S. Wicha: Targeting Cancer Stem Cells Using Immunologic Approaches. STEM CELLS 33:2085—2092, 2015.
  5. Mark E.P. Prince, Huimin Tao, Jeffrey S. Moyer, Lin Lu, John Owen, Martin Etigen, Fang Zheng, Alfred E Chang, Jianchuan Xia, Gregory Wolf, Max S Wicha, Shiang Huang, Qiao Li: Evaluation of the immunogenicity of ALDHhigh human head and neck squamous cell carcinoma cancer stem cells in vitro. Oral Oncology, 59:30-42, 2016.
  6. Yangyang Hu, Lin Lu, Yang Xia, Alfred E. Chang, John Owen, Jeffrey S. Moyer, Mark E.P. Prince, Fu Dai, Yangyi Bao, Jian-chuan Xia, Shiang Huang, Max S. Wicha, Qiao Li: Therapeutic efficacy of cancer stem cell vaccines in the adjuvant setting. Cancer Res, 76:4661-72, 2016.
  7. Yang Xia, Huimin Tao, Quanning Chen, Yangyang Hu, Li Zhou, Yi Wang, Yangyi Bao, Shiang Huang, Xiubao Ren, Fu Dai, Qiao Li, Alfred E. Chang: IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways. Oncotarget, 7:60461-60474, 2016.
  8. Zheng F, Dang J, Zhang H, Xu F, Ba D, Zhang B, Cheng F, Chang AE, Wicha MS, Li Q,: Cancer stem cell vaccination with PD-L1 and CTLA-4 blockades enhances the eradication of melanoma stem cells. Journal of Immunotherapy 41: 361-368, 2018.
  9. Scheetz L, Park C, Li Q, Lowenstein PR, Castro MG, Schwendeman, A, and Moon JJ. Engineering strategies for personalized cancer immunotherapy: a paradigm shift. Nature Biomedical Engineering 3:768–782, 2019.
  10. Ruan S, Lin M, Zhu Y, Lum LG, Thakur A, Chen Y, Jin R, Shao W, Zhang Y, Hu Y, Huang S, Hurt EM, Chang AE, Wicha MS, and Li Q.: Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis. Cancer Res 80:771–83, 2020.