Publications

Explore significant publications from the Translational Tumor Immunology Lab.

Key Publications

  1. Qin Pan, Qiao Li, Shuang Liu, Ning, XiaoLian Zheng, Yingxin Xu, Alfred E. Chang, Max S. Wicha: Targeting Cancer Stem Cells Using Immunologic Approaches. STEM CELLS 33:2085—2092, 2015.
  2. Mark E.P. Prince, Huimin Tao, Jeffrey S. Moyer, Lin Lu, John Owen, Martin Etigen, Fang Zheng, Alfred E Chang, Jianchuan Xia, Gregory Wolf, Max S Wicha, Shiang Huang, Qiao Li: Evaluation of the immunogenicity of ALDHhigh human head and neck squamous cell carcinoma cancer stem cells in vitro. Oral Oncology, 59:30-42, 2016.
  3. Yangyang Hu, Lin Lu, Yang Xia, Alfred E. Chang, John Owen, Jeffrey S. Moyer, Mark E.P. Prince, Fu Dai, Yangyi Bao, Jian-chuan Xia, Shiang Huang, Max S. Wicha, Qiao Li: Therapeutic efficacy of cancer stem cell vaccines in the adjuvant setting. Cancer Res, 76:4661-72, 2016.
  4. Yang Xia, Huimin Tao, Quanning Chen, Yangyang Hu, Li Zhou, Yi Wang, Yangyi Bao, Shiang Huang, Xiubao Ren, Fu Dai, Qiao Li, Alfred E. Chang: IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways. Oncotarget, 7:60461-60474, 2016.
  5. Zheng F, Dang J, Zhang H, Xu F, Ba D, Zhang B, Cheng F, Chang AE, Wicha MS, Li Q,: Cancer stem cell vaccination with PD-L1 and CTLA-4 blockades enhances the eradication of melanoma stem cells. Journal of Immunotherapy 41: 361-368, 2018.
  6. Scheetz L, Park C, Li Q, Lowenstein PR, Castro MG, Schwendeman, A, and Moon JJ. Engineering strategies for personalized cancer immunotherapy: a paradigm shift. Nature Biomedical Engineering 3:768–782, 2019.
  7. Ruan S, Lin M, Zhu Y, Lum LG, Thakur A, Chen Y, Jin R, Shao W, Zhang Y, Hu Y, Huang S, Hurt EM, Chang AE, Wicha MS, and Li Q.: Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis. Cancer Res 80:771–83, 2020.
  8. Najafabadi AH, Zhang J, Aikins ME, Zeynab, Abadi ZIN, Liao F, Qin Y, Okeke EB, Scheetz LM, Nam J, Xu Y, Adams D, Lester P, Hetrick T, Schwendeman A, Wicha MS, Chang AE, Li Q, and Moon JJ. Combination immunotherapy against cancer stem cells using synthetic high-density lipoprotein nanodiscs. Nano Letters.
  9. Xia L, Wen L, Qin Y, Dobson H, Zhang T, Comer FI, Hinrichs MJ, Obers MD, Coats SR, Chang AE, Liu Y, Bao Y, Wicha MS, and Li QHER2-targeted antibody drug conjugate induces host immunity against cancer stem cells. Cell Chem Biol. 2021 Mar 3:S2451‐9456(21)0009 doi:10.1016/j.chembiol.2021.02.013. Epub ahead of print. PMID: 33711257.
  10. Dobson HE, Ruan S, Chang AE, Wicha MS, Li Q. Targeting cancer stem cells via integrin ß4. Oncotarget. 2021 Aug 31;12(18):1850-1858.10.18632/oncotarget.27977. PMID: 34504657; PMCID: PMC8416562.