Clinical Informatics and Technology

Clinical informatics and technology

Current Studies

MI-BP: mHealth to Improve Blood Pressure Control in Hypertensive African Americans

Lorraine Buis, PhD, MSI, Principal Investigator

Funded by the National Institutes of Health, National Heart, Lung, and Blood Institute ($2,970,128)

This study seeks to improve hypertension-related outcomes in a cohort of African Americans with uncontrolled hypertension between the ages of 25 and 55, through the use of MI-BP, a comprehensive, multiple health behavior change mobile intervention. This research is guided by three specific aims:

  • Determine the effect of MI-BP on blood pressure control at one year, compared with usual care controls, in a one-year RCT.
  • Determine the effect of MI-BP on secondary outcomes (physical activity, sodium intake, medication adherence) compared to usual care controls, in a one-year RCT.
  • Evaluate the cost-effectiveness of MI-BP compared to usual care methods.

Early Audiology Referral in Primary Care (EAR-PC): Improving Detection of Hearing Loss

Philip Zazove, M.D., Principal Investigator

Funded by the National Institutes of Health, National Institute on Deafness and Other Communication Disorders, Department of Health and Human Services ($1,624,469)

Dr. Zazove is lead investigator of this R21/R33 study, which seeks to increase hearing loss screenings for patients 55 and older by utilizing electronic clinical management tools in primary care setting and multimedia. The MiChart research team has designed a Best Practice Alert (BPA) which notifies primary care providers (PCPs) of HL assessment opportunities and allows clinicians to refer directly and efficiently to audiology specialists. The multimedia project, guided by Micheleen Hashikawa, M.D., also created a video to address physicians’ mental models of hearing loss. The investigation has expanded to look at patients’ decision-making around hearing testing and adoption of hearing aids. The EAR-PC study has partnered with the Beaumont Family Medicine network and Elie Mulhem, M.D., Associate Professor, Oakland University William Beaumont School of Medicine to successfully include 5,500 patients in the pilot study. Dr. Zazove anticipates over 20,000 patients in the R33 phase.

The research is guided by three aims, to:

  • Evaluate whether the EAR-PC program increases PCP identification of patients with mild to moderate HL compared to baseline data.

  • Evaluate whether the EAR-PC program increases appropriate PCP referral of patients with mild to moderate HL to audiology specialists.

  • Utilize both qualitative and quantitative inquiry to investigate how successful PCPs implement the intervention, identifying processes and tools that will allow this project to successfully scale

Speaking Their Language: Using Social Media And Texting To Create An Adolescent-Centered Approach To Healthy Weight Gain During Pregnancy

Tammy Chang, MD, MPH, MS, Principal Investigator

Funded by the National Institutes of Health, Eunice Kennedy Shriver National Institute Of Child Health & Human Development

This mixed-methods study will develop an adolescent-centered tailored eHealth intervention to reduce excess pregnancy weight gain. Researchers will integrate quantitative analyses using nationally representative data  with social media mining and corresponding qualitative interviews with pregnant and postpartum adolescents. The goals of the study are to:

  • Determine which US pregnant adolescents (aged ≤21 years) are at high risk for significant excess pregnancy weight gain;
  • Identify the baselin knowledge, beliefs, and factors that influence excess pregnancy weight gain among adolescents
  • Design and test a scalable healthy diet and exercise eHealth intervention tailored to at-risk pregnant adolescents.

Decision Aid to Technologically Enhance Shared Decision Making (DATES)

Masahito Jimbo, M.D.,Ph.D., M.P.H., Principal Investigator

Funded by National Institutes of Health

Since Colorectal Web (CW) is an interactive decision aid to facilitate Shared Decision Making for average-risk adults needing colorectal cancer screening, this randomized controlled study will compare CW to a non-interactive web-based CRC screening program.

Modeling Professional Attitudes and Teaching Humanistic Communication in Virtual Reality (MPathic VR)

Michael D. Fetters, M.D., M.P.H., M.A., Principal Investigator

Funded by The National Institutes of Health

The M-Pathic VR II project will rigorously evaluate the extent that the newly successful "virtual reality" software program (developed in Phase I) can enhance medical school curricula in professionalism, empathy, and in patient-centeredness (using verbal and non-verbal communication skills) as well as the ACGME competencies when treating a terminally ill cancer patient.

Enhancing the Sustainability of Depression Disease Management Support for Primary Care

Michael S. Klinkman M.D., M.S., Principal Investigator

Funded by Ethel & James Flinn Foundation

Designing a more efficient self-management component for M-DOCC. During the first six months of the project, we will create a series of self-management modules that can be delivered in paper or Web-based format, each linked to a self-assessment instrument, and integrate this into the M-DOCC case management software. During Year 2, we will evaluate the success of this new module by tracking the proportion of new enrollees who complete each module, identify a goal, make progress, or reach a goal, as well as the length of time enrollees remain active in the program. We will also conduct qualitative interviews of enrollees to assess its perceived value.

MyVoice- Real-time Text Messaging Polling to give Adolescents a Voice

Tammy Chang, MD, MPH, MS, Principal Investigator

There is a critical need to understand the opinions and needs of adolescents regarding issues that affect them. Until interventions and policies are tailored to meet adolescents’ needs, they will continue to experience worse health and social outcomes. Thoughts and beliefs of adolescents are difficult to illicit through traditional surveys and interviews because they often have difficulty verbalizing their beliefs due to their ongoing cognitive, social, and emotional development, and limited health literacy. We will use text messaging, a platform used by nearly all teens, to ask weekly open-ended and multiple-choice questions to allow adolescents to ‘speak’ to researchers in real-time using a method they are familiar with.

MCubed study page
MyVoice logo

My Voice study site

Great Lakes Research Into Practice Network (GRIN)

Michael S. Klinkman M.D., M.S., Co-Investigator

Funded by Michigan Academy of Family Physicians Foundation

GRIN is a statewide primary care research network of office practices in family practice, internal medicine, pediatrics, obstetrics and gynecology, and independent-practice nursing. Its goal is to assist primary care researchers to conduct studies in primary care settings. This, in turn, will help practitioners apply research findings that are reflective of the complexities of primary care practice.


Media and Infographics

Video abstract for Timothy Guetterman's 2017 MPathic-VR validation study in Advances in Medical Education and Practice


U-M Family Medicine Research Trailers #4: Text message alerts for medication adherence 

Recent Publications

  1. Alwashmi MF, Hawboldt J, Davis E, Fetters MD. The Iterative Convergent Design for Mobile Health Usability Testing: Mixed-Methods Approach. JMIR mHealth and uHealth. 2019;7(4). doi:10.2196/11656.
  2. Dejonckheere M, Nichols LP, Vydiswaran VV, et al. Using Text Messaging, Social Media, and Interviews to Understand What Pregnant Youth Think About Weight Gain During Pregnancy. JMIR Formative Research. 2019;3(2). doi:10.2196/11397.
  3. Buis LR, Mccant FA, Gierisch JM, et al. Understanding the Effect of Adding Automated and Human Coaching to a Mobile Health Physical Activity App for Afghanistan and Iraq Veterans: Protocol for a Randomized Controlled Trial of the Stay Strong Intervention. JMIR Research Protocols. 2019;8(1). doi:10.2196/12526.
  4. Buis LR, Dawood K, Kadri R, et al. Improving Blood Pressure Among African Americans With Hypertension Using a Mobile Health Approach (the MI-BP App): Protocol for a Randomized Controlled Trial. JMIR Research Protocols. 2019;8(1). doi:10.2196/12601.
  5. Moin T, Damschroder LJ, Auyoung M, et al. Results From a Trial of an Online Diabetes Prevention Program Intervention. American Journal of Preventive Medicine. 2018;55(5):583-591. doi:10.1016/j.amepre.2018.06.028.
  6. Senteio C, Veinot T, Adler-Milstein J, Richardson CR. Physicians’ perceptions of the impact of the EHR on the collection and retrieval of psychosocial information in outpatient diabetes care. International Journal of Medical Informatics. 2018;113:9-16. doi:10.1016/j.ijmedinf.2018.02.003.
  7. Braciszewski JM, Wernette GKT, Moore RS, et al. Developing a tailored substance use intervention for youth exiting foster care. Child Abuse & Neglect. 2018;77:211-221. doi:10.1016/j.chiabu.2018.01.013.

See more

  1. DeJonckheere MNichols LP, Moniz MH, Sonneville KR, Vydiswaran VGV, Zhao X, Guetterman TC, Chang T. MyVoice National Text Message Survey of Youth Aged 14 to 24 Years: Study Protocol. JMIR Res Protoc. 2017 Dec 11;6(12):e247. doi: 10.2196/resprot.8502.
  2. Buis LR, Roberson DN, Kadri R, et al. Utilizing Consumer Health Informatics to Support Management of Hypertension by Clinical Pharmacists in Primary Care: Study Protocol. JMIR Research Protocols. 2017;6(10). doi:10.2196/resprot.8059.
  3. Wan ES, Kantorowski A, Homsy D, Teylan M, Kadri R, Richardson CR, et al. Promoting physical activity in COPD: Insights from a randomized trial of a web-based intervention and pedometer use. Respiratory Medicine. 2017 Sept; 130:102-110. doi: 10.1016/j.rmed.2017.07.057.
  4. Guetterman TC, Kron FW, Campbell TC, Scerbo MW, Zelenski AB, Cleary JF, Fetters MD. Initial construct validity evidence of a virtual human application for competency assessment in breaking bad news to a cancer patient. Advances in Medical Education and Practice. Available online 25 July 2017, 8:505—512. doi: 10.2147/AMEP.S138380
  5. Rai M, Moniz MH, Blaszczak J, Richardson CR, Chang T. Real-Time Data Collection Using Text Messaging in a Primary Care Clinic. Telemed J E Health. 2017 May 24. doi: 10.1089/tmj.2017.0022. [Epub ahead of print]
  6. Braciszewski JM, Tran TB, Moore RS,Bock BC, Tzilos GK, Chamberlain P, Stout RL. Developing a Tailored Texting Preventive Intervention: A Card Sort Methodology. Journal of Applied Biobehavioral Research. 19 April 2017. doi: 10.1111/jabr.12060 [Epub ahead of print]
  1. Bian RR, Piatt GA, Sen A, Plegue MA, De Michele ML, Hafez D, Czuhajewski CM, Buis LR, Kaufman N, Richardson CR. The Effect of Technology-Mediated Diabetes Prevention Interventions on Weight: A Meta-Analysis. J Med Internet Res 2017;19(3):e76 DOI: 10.2196/jmir.4709
  2. Buis L, Hirzel L, Dawood RM, et al. Text Messaging to Improve Hypertension Medication Adherence in African Americans From Primary Care and Emergency Department Settings: Results From Two Randomized Feasibility Studies.  J Med Internet Res. 2017 Feb; 5(2). doi: 10.2196/mhealth.6630
  3. Schwartz DD, Stewart SD, Aikens JE, et al. Seeing the Person, Not the Illness: Promoting Diabetes Medication Adherence Through Patient-Centered Collaboration. Clinical Diabetes 2017 Jan; 35(1): 35-42. doi: 10.2337/cd16-0007


Collaborative Partners and External Affiliations


    Primary Investigators