Dr. Manczak’s program of research examines the biological and psychological mechanisms through which experiences during childhood and adolescence confer risk for mental and physical health disorders. She is especially interested in how important social relationships affect immune processes that in turn increase risk for depression in adolescence; however, my work also examines risk across other developmental periods (e.g., adulthood, prenatal) and considers a variety of additional biological pathways (e.g., epigenetic modifications, somatic fitness).