Biography
Srijan Sen is the Director of the Frances and Kenneth Eisenberg and Family Depression Center and the Frances and Kenneth Eisenberg Professor of Depression and Neurosciences.
Dr. Sen’s research focuses on the interactions between genes and the environment and their effect on stress, anxiety, and depression. His research includes leadership of the large Intern Health Study, which focuses on studying physicians in their first year of post-medical school training using genomics, mobile technology and other tools to understand how stress leads to depression. As of February 2021, the study includes data from more than 25,000 interns at over 100 U.S. and Chinese teaching hospitals
Areas of Interest
- Depression
- Genes
- Gene x Environment Interactions
- Medical Education
- Digital Psychiatry
Featured News

Support from others in stressful times can ease impact of genetic depression risk
Study in first-year doctors and recently widowed older adults shows greatest impact of social support in those with highest polygenic risk scores for depression

In stressful jobs, depression risk rises with hours worked, study in new doctors finds
In “emulated” clinical trial, longer work weeks were strongly linked to larger rise in depression symptoms, pushing some first-year resident physicians into moderate or severe depression range.

U-M study: Depression incidence and factors among residents are similar in China and US
Though a world apart, first-year residents in the United States and China have more in common than they might imagine, including bouts of depression, a new study suggests.

U-M Depression Center enters 20th year with new director and focus on next-generation research
Srijan Sen, M.D., Ph.D., takes the reins from founding director John Greden, M.D.

Irregular Sleep Connected to Bad Moods and Depression, Study Shows
The more variation in wake up and sleep time, the worse mood and more chance of depression symptoms.
Credentials
- Yale (residency)
- University of Michigan (MD and PhD)
- Oxford University (undergrad)
- Cornell University (undergrad)