Research Symposium

      U-M Internal Medicine Research Symposium 3

The Department of Internal Medicine Annual Research Symposium showcases the research projects completed by our residents and provides an opportunity for fellows and students, as well as faculty, to present their work and interact with department members. A focal event of the symposium is Grand Rounds delivered by an invited outstanding physician scientist.

2021 Research Symposium 

The Department of Internal Medicine's annual research symposium was held virtually this year. Please see the program below. 

Ben Margolis Research Award Winner

Yun Han, PhD

Yun Han, PhD 
Assistant Research Scientist, Division of Nephrology

Yun Han, PhD is an Assistant Research Scientist in the Division of Nephrology and at Kidney Epidemiology and Cost Center. She obtained her MS in health policy and management at the University of California, Los Angeles and received her PhD degree in social and administrative sciences in pharmacy at the University of Michigan. Her research interests center around health services and outcomes research and pharmacoepidemiology.

Dr. Han has extensive data analysis experience on large and complex healthcare data, such as claims data, clinical data and survey data. She assists in the work for developing kidney disease surveillance systems. She has been involved in the CDC CKD Surveillance Project and the United States Renal Data System project. In particular, Dr. Han has been recently focused on assessing pharmacotherapies in kidney disease and explore the impact of environmental and social determinants of health on kidney health using spatial analysis techniques.


Department of Internal Medicine Senior Medical Residents
May 5-7, 2021

To view the Department of Internal Medicine 2021 Senior Resident Research Symposium, click here.

Department of Internal Medicine Faculty, Fellows, and Students
May 7, 2021

May 7, 2021

Virtual Poster Session

(U-M faculty and staff can view the virtual poster session (Basic Science, Clinical, Health Services, Translational) on the department's intranet. Level-2 password required). Click here.

Plenary Session, 9:00 – 11:30am

  • 9:00 am, Welcome and Introductions - Vibha Lama, MD, MS - Vice Chair, Basic and Translational Research, Internal Medicine
  • 9:10, Michigan Medicine Research VisionSteve Kunkel, PhD - Executive Vice Dean for Research and Chief Scientific Officer, Michigan Medicine
  • 9:35, State of Internal Medicine Research - John Carethers, MD, MACP - Chair, Department of Internal Medicine, Michigan Medicine

Plenary Oral Presentations

  • 9:50, CCKBR Containing Neurons in the VMN Regulate Lipid and Glucose Metabolism in Mice - Alison Affinati, MD, PhD
  • 10:00, Genomic Epidemiology of SARS-CoV-2 at the University of Michigan in Fall 2020 - Andrew Valesano, BS
  • 10:10, The potential Impact of Removing the eGFR Race Coefficient on CKD Care Practices Among Black Veterans Receiving Care in U.S. -  Yun Han, PhD
  • 10:20, Fewer Combination Ipilimumab/Nivolumab Doses May Predict Survival Outcomes in Advanced Stage Melanoma - Vincent Ma, MD
  • 10:30, How to Maximize Pulmonary Oxygen Uptake: A Systematic Analysis of Mathematical Models Representing Ventilation-Perfusion Matching - Andrew Marquis, BS
  • 10:40, SARS-CoV-2 Antibodies Correlate with COVID-19 Immunity and Persist After Mild Infection - Charles Schuler, MD
  • 10:50, Diagnostic and Prognostic Value of Soluble Urokinase Plasminogen Activator Receptor (Supar) in Cardiac Ischemia - Rafey Feroze, MD
  • 11:00, Race and Outcomes After Contemporary Percutaneous Coronary Intervention: Insights from the Blue Cross Blue Shield of Michigan Cardiac Consortium  - Stephanie Spehar, MD
  • 11:10, Expression of PLK-1 in Nodular Lymphocyte Predominant Hodgkin Lymphoma Correlates with Disease Stage, and Selective PLK-1 Inhibition may Constitute a Viable Therapeutic Alternative - Jonathan Weiss, MD
  • 11:20, Closing Remarks | Department of Internal Medicine Benjamin Margolis MD Outstanding Abstract Award
  • 11:30, Morning Session Adjourn

Grand Rounds – Keynote Speaker Session,12:00 – 1:00pm

12:00 pm, Academic Medicine: Mission Critical to Public Health Crises - Mary E. Klotman, MD - Dean and Vice Chancellor, Duke University School of Medicine; Chief Academic Officer, Duke Health

Concurrent Thematic Mini Symposium, 1:30 – 4:45pm

Advances in Clinical Medicine, 1:30-3:00
Co-Chairs  – Dr. Lona Mody and Dr. Santhi Ganesh

  • 1:30, Patient Stratification using RNA-seq Data and Consensus Clustering Algorithm as a Tool for Precision Medicine of Patients with Nephrotic Syndrome - Fadhl Alakwaa, PhD
  • 1:40, Calcium Channel Blocker Use in Patients with Heart Failure with Reduced Ejection Fraction and Comorbid Atrial Fibrillation  - George Cholack, BS
  • 1:50, Transplant Clinician Opinions on Use of Race in The Estimation of Glomerular Filtration Rate: A National U.S. Survey Study - Mona Doshi, MD
  • 2:00, High-frequency Temperature Monitoring with Wearable Sensors and Computational Analysis Enables Early Detection of Febrile Adverse Events in Hematologic Cancer Patients - Christopher Flora, PhD
  • 2:10, Effectiveness of a Multicomponent Intervention to Reduce Multidrug-Resistant Organisms in Nursing Homes: A Cluster Randomized Trial - Kyle Gontjes, MPH
  • 2:20, Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients with Active Rheumatoid Arthritis  - Meriah Moore, MD
  • 2:30, Analysis of Management Strategies Following Slightly Out of Range INRs: Watchful Waiting vs. Any Dose Changes - Hallie Remer, BS
  • 2:40, Next Generation Sequencing of Veteran Cancers Uncover Mutations Indicative of Potentially Pathogenic Germline Variants and Need for Germline Testing - Anthony Scott, MD, PhD
  • 2:50, Genome-Wide Association Study of Hepatic Cirrhosis identifies multiple causal variants and genes  - Angel Chu, MS
  • 3:00, Closing Remarks     

Metabolism, Microbiome, Obesity, 1:30-3:00
Co-Chairs – Dr. Peter Arvan and Dr. Liz Speliotes

1:30, Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes - Maroof Alam, PhD
1:40, Antibiotic Administration Causes Metabolic Changes in Mice Predominantly Through Microbiome Modulation Rather Than Primary Behavioral Changes - Kale Bongers, MD, PhD, MA
1:50, Intestinal-derived FGF15 protects against bile acid toxicity following sleeve gastrectomy- Nadejda Bozadjieva Kramer, PhD
2:00, Inhibition of Angiopoietin-like 3 (ANGPTL3) reduces adipose tissue insulin resistance in subjects with familial partial lipodystrophy - Maria Foss de Freitas, MD, PhD
2:10, Molecular and cellular features associated with NAFLD candidate genes and variants - Brian Halligan, PhD
2:20, Thrombospondin-1 promotes diaphragm remodeling and contractile dysfunction in obesity - Romil Kaul Verma, BS: MCDB and EEB
2:30, Body composition, gluconeogenesis, and hepatic inflammation in obese mice with Klebsiella  - Avnee Kumar, MD
2:40, Knockout of Lyplal1 in mice leads to sex-specific changes in accumulation of fat and metabolic parameters on a Western diet - Annapurna Kuppa, MS
2:50, Synergism in Protein Quality Control Pathways Maintain Pancreatic Islet Alpha Cell Mass and Function - Rachel Reinert, MD, PhD
3:00, Closing Remarks

Investigating COVID-19, 3:15-4:45
Co-Chairs – Dr. Rodica Busui and Dr. Hallie Prescott

3:15, Post-Discharge Clinical Care During the COVID-19 Pandemic: A Multihospital Cohort Study - Christopher Smith, MD
3:25, The Impact of COVID-19 on End-Stage Renal Disease (ESRD) Quality Measures: Implications for Public Reporting - Claudia Dahlerus, PhD
3:35, Did Clostridioides difficile testing and infection rates change during the COVID-19 pandemic? - Armani Hawes, BA
3:45, When Planning Meets Reality: COVID-19 Inter-pandemic Survey of Michigan Nursing Homes  - Karen Jones, MPH
3:55, Critical care experiences and anxiety among family members: A qualitative study - Amanda Blok, PhD, RN
4:05, Factors influencing code status of patients hospitalized with COVID-19 - Blair Lenhan, MD
4:15, Characterizing Venous Thromboembolism in Patients with Moderate to Severe COVID-19 - Annika Tekumulla, Undergraduate Student
4:25, Variation in COVID-19 disease severity at hospital admission over time and across hospitals: A multi-institution cohort of Michigan hospitals - Max Wayne, MD
4:35, Closing Remarks


Basic and Translational Discoveries, 3:15 – 4:45
Co-Chair – Dr. Goutham Narla and Dr. Michelle Kahlenberg

3:15, Antibiotic-Mediated Potentiation of Oxygen-Induced Lung Injury Is Preceded by Enterococcal Dominance in The Murine Gut - Jennifer Baker, BS
3:25, ASCL3, a New Regulator of Vascular Smooth Muscle Cells Homeostasis - Minerva Garcia-Barrio, PhD
3:35, Murine iNOS expression is essential for antifungal defenses in kidneys during disseminated cryptococcosis – Kristie Goughenour, PhD
3:45, The Mechanistic Basis for use of Anti-CD6 as a Novel Form of Cancer Immunotherapy - Mikel Gurrea Rubio, PhD
3:55, LC/MS analysis reveals Remodeling of Renal Cortical Mitochondrial Cardiolipins in Diabetic Kidney Disease - Chenchen He, PhD
4:05, Dual-specific phosphatase 1 (DUSP1) mediates bortezomib anti-fibrotic actions through a proteasome-independent mechanism - Loka Raghu Kumar Penke, PhD
4:15, Characterization of PP2A-C carboxymethylation as a potential prognostic and predictive marker in prostate cancer - Jaya Sangodkar, PhD
4:25, The Large Conductance Potassium (BK) Channel Promotes Myofibroblast Differentiation Through Increases in Calcium Signaling - Anne Scruggs, BS, MPH
4:35, Adult and pediatric fibromuscular dysplasia are genetically distinct dysplasia-associated arterial diseases - Yu Wang, PhD
4:45, Closing Remarks

Research Symposium Archive