While we are a clinical department within the U-M Medical School, the Department of Internal Medicine is also home to more than 130 basic, translational, and clinical research faculty members. Spread across 13 divisions, our research community successfully competes for funding from national agencies, foundations, and industry sponsored projects. Our scientists are dedicated to identifying and implementing real solutions to redefine how we practice medicine. We understand that great science can dramatically transform the lives of our patients here in Michigan and beyond.      


Vibha Lama, MD, MSVice Chair, Basic and Translational Research
Rodica Pop-Busui, MD, PhD - Vice Chair, Clinical Research


Michigan Internal Medicine research

U-M, which has ranked No. 1 in research volume among the nation’s public universities for the past ten years, reported $1.58 billion in research volume during 2021, which led to many important advancements including those addressing the COVID-19 pandemic. Nearly a third of that funding comes from the work of internal medicine faculty. In 2021, the Department of Internal Medicine competed for and obtained $216 million in research support and published more than 2,300 research publications.


Department of Internal Medicine researchers across our specialties are conducting COVID-19 research to learn more about the disease and to develop improved and more personalized treatment methods. The below articles highlight some of their work.

High Blood Sugar and suPAR Levels Independently Worsen COVID-19 Outcomes

Salim Hayek, MD; Matthias Kretzler, MD; Rodica Pop-Busui, MD, PhD; and team investigate the role of inflammatory biomarkers in hospitalized COVID patients and uncover risk factors for worse health outcomes in those with diabetes. Read more.

Fighting COVID-19 with Milk?

Jonathan Sexton, PhD and team investigate the antiviral properties of cow milk protein against variants of SARS-CoV-2. Read more.

ZIP Codes Matter When It Comes to Severe COVID-19

Renuka Tipirneni, MD, MSc; Monita Karmakar, PhD, MS; and Hallie Prescott, MD, MSc find that people who lived in the most underprivileged ZIP codes were more likely to have severe symptoms; however, they were no more likely to die than those from more privileged areas, and no less likely to go back to their own homes instead of a nursing home. Read more.

Pandemic Disrupted Many Older Adults’ Health Care Plans

Jeffrey Kullgren, MD, MPH, MS finds nearly one in three people over 50 with a scheduled procedure, or primary care or dental visit in 2021, had a COVID-related delay. Read more.

Disruption in Lung Cell Repair May Underlie Acute Respiratory Distress Syndrome in COVID-19 and Other Respiratory Diseases

Christopher Ting, MD; Rachel Zemans, MD; and their team's research lay the groundwork for the development of new therapies to improve survival and prevent chronic lung disease in COVID-19 and non-COVID-19 acute respiratory distress syndrome. Read more.


Learn more below about the research being conducted across our 13 divisions, our research centers, our annual research symposium, and our rich research history.


U-M researchers have access to robust services, equipment, testing, and technologies. Whether you are engaged in basic science research or clinical trials, U-M provides the support you need:


Michigan Research Experts is a searchable database of research expertise across the University of Michigan, developed by the Medical School Office of Research and custom-tailored for our research community to foster collaboration on campus and around the world.