The clinical and translational research programs outlined below are at the disposal of all cardiology fellows at the University of Michigan. Research opportunities are uniformly strong across disciplines, and fellows are encouraged to create new collaborations across the schools and institutes at the University. Over the course of training, fellows have been known to publish in high impact journals such as the Journal of the American College of Cardiology, Circulation, the Journal of the American Medical Association, and the New England Journal of Medicine.
Formal Clinical Research Programs
- Robert Wood Johnson Clinical Scholars Program
- Institute for Health Policy and Innovation
- Michigan Cardiovascular Outcomes Research and Reporting Program (MCORRP)
- Value Based Insurance Design
- Center for Health Outcomes and Policy
- Blue Cross and Blue Shield of Michigan Vascular Interventions Collaborative (BMC2)
- University of Michigan Center for Arrhythmia Research
Ongoing Clinical Trials
Clinical Registries
- MEDFIT — Preventive Cardiology Patient Registry
- IRAD — International Registry on Aortic Dissection
- CSR — Cardiac Sarcoid Global Registry
- FMD — Global Fibromuscular Dysplasia Registry
- MAQI — Michigan Anticoagulation Quality Improvement Registry
- PHS — Project Healthy Schools Initiative
- BRIDGE — Post Discharge Cardiac Patient Management Registry
Basic Science Research Opportunities
- Signaling pathways in ischemia-reperfusion injury
- CD39 ectonucleotidase in coagulation and inflammation
- PAI-1 in atherosclerosis and thrombosis
- Leptin in thrombosis and atherosclerosis
- Genetic modifiers of obesity
- Glycophingolipids in vascular disease
- Molecular mechanisms of cardiomyocyte differentiation from embryonic precursors
- Role of troponin I in the adult cardiac myocyte contractile response to PKC
- Molecular mechanisms regulating smooth muscle proliferation
- Role of cardiac renin-angiotensin system in myocyte hypertrophy
- Novel genetic modifiers of thrombosis
- Structure and function of voltage-gated sodium channels
- Mechanisms involved in obesity-induced hypertension
- Regulation of protein folding
- Protein-protein interaction domains in cell signaling
- Basic mechanisms of hypertrophic cardiomyopathy
- G-protein mediated pathways in cardiovascular disease
- Sympathetic nervous system and adrenergic responsiveness in aging
- Inflammation in venous thrombosis
- Genetic modifiers of hypertension
- Matrix metalloproteinases in vascular disease
- Tools for measuring cardiovascular complications of diabetes
- Basic mechanisms of arrhythmia